Results 111 to 120 of about 4,807 (209)
The Many Hats of Sonic Hedgehog Signaling in Nervous System Development and Disease. [PDF]
, 2016 Sonic hedgehog (Shh) signaling occurs concurrently with the many processes that constitute nervous system development. Although Shh is mostly known for its proliferative and morphogenic action through its effects on neural stem cells and progenitors, it ...
Belgacem, Yesser H +4 more
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Regenerative Medicine for the Aging Brain [PDF]
, 2014 In the central nervous system, cholinergic and dopaminergic (DA) neurons are among the cells most susceptible to the deleterious effects of age. Thus, the basal forebrain cholinergic system is known to undergo moderate neurodegenerative changes during ...
Goya, Rodolfo Gustavo +3 more
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A novel variation in the LMX1B gene with nail-patella syndrome
Pathology - Research and PracticeNail-patella syndrome (NPS; OMIM #161200) is an autosomal dominant disorder characterized by developmental defects in dorsal limb structures, kidneys, and eyes. The incidence of NPS is attributed to variations in the LMX1B gene. In this report, we present a novel LMX1B variation identified in a Chinese family affected by NPS. The proband, a 15-year-old
Lu Zhang +8 more
openaire +2 more sources
Acta Dermato-Venereologica, 2019 Nail-patella syndrome is an autosomal dominant disorder characterized by nail dysplasia and skeletal anomaly. Some patients have been shown to have ultrastructural abnormalities of the glomerular basement membrane that result in nephrosis.
Satoru Shinkuma +9 more
doaj +1 more source
Ihmisen mesenkymaalisten kantasolujen erilaistaminen dopaminergisiksi neuroneiksi aivoelektrodimateriaaleilla [PDF]
, 2016 Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into various cell types depending on their environment, but cannot undergo neurogenesis in normal conditions.
Mynttinen, Elsi
core
Role of Dmrt5 during development of midbrain dopaminergic progenitors
, 2011 This thesis investigates the previously un-described role of Dmrt5, a zinc-finger transcription factor, in ventral midbrain development. The spatio-temporal expression pattern of Dmrt5, described for the first time in this thesis, suggests that Dmrt5 may
Farley, Emma Kirsten +1 more
core +1 more source
PLoS ONE, 2015 Directed methods for differentiating human embryonic stem cells (hESCs) into dopaminergic (DA) precursor cells using stromal cells co-culture systems are already well established. However, not all of the hESCs differentiate into DA precursors using these
Mi-Sun Lim +9 more
doaj +1 more source
Brain Research BulletinElectroacupuncture (EA), a modern adaptation of traditional acupuncture, has shown promising analgesic effects across various pain models. However, the underlying central mechanisms remain insufficiently characterized.
Jiawei Zhang +13 more
doaj +1 more source
Progress in Pathogenesis of Proteinuria
International Journal of Nephrology, 2012 Aims. Proteinuria not only is a sign of kidney damage, but also is involved in the progression of renal diseases as an independent pathologic factor. Clinically, glomerular proteinuria is most commonly observed, which relates to structural and functional
Aihua Zhang, Songming Huang
doaj +1 more source