Results 111 to 120 of about 3,237 (188)

LMX1B wt Allele [PDF]

, 2020
openaire   +1 more source

The role of LMX1B and PITX2 in anterior segment development and adult ocular function

, 2001
Several congenital syndromes associated with anterior segment (AS) anomalies can lead to impaired vision and glaucoma, such as nail-patella syndrome (NPS), caused by mutations in the LIM homeodomain transcription factor LMX1B and Axenfeld-Rieger\u27s ...
Pressman, Carolyn Leah
core   +1 more source

The role of Lmx1b in the control of dorsoventral compartmentalization in the distal mesenchyme of the developing mouse limb

, 2005
Lmx1b encodes a LIM-homeodomain transcription factor required for dorso-ventral (D-V) patterning in the mesenchyme of the vertebrate limb. In the absence of Lmx1b function, limbs exhibit a bi-ventral pattern indicating that Lmx1b is required for cells to
Qiu, Qiong
core   +1 more source

Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons.

Acta biochimica et biophysica Sinica, 2013
Serotonin (5-HT) neurons synthesize a variety of peptides. How these peptides are controlled during development remains unclear. It has been reported that the co-localization of peptides and 5-HT varies by species. In contrast to the situations in the rostral 5-HT neurons of human and rat brains, several peptides do not coexist with 5-HT in the rostral
Rui, Yan, Tianwen, Huang, Zhiqin, Xie, Guannan, Xia, Hui, Qian, Xiaolin, Zhao, Leping, Cheng   +6 more
openaire   +1 more source

Differential vulnerability of cochlear nuclei to Lmx1 deficiency: abnormal patterning and implications for auditory circuitry. [PDF]

Neurosci Lett
Iskusnykh I, Yamoah EN, Chizhikov VV, Fritzsch B.   +3 more
europepmc   +1 more source

Transient Nephrotic Syndrome in an Infant With Heterozygous Variants of Uncertain Significance in LMX1B and TTC21B. [PDF]

Cureus
Greisch A, Hennaut E, Ismaili K.
europepmc   +1 more source

The origin and evolution of dorsal determination mechanisms in vertebrate paired appendages. [PDF]

Curr Biol
Hawkins MB, Zdral S, Naranjo S, Juliá M, Sánchez-Martín M, Daane JM, Cumplido N, Jandzik D, Medeiros DM, McMenamin SK, Harris MP, Tena JJ, Ros MA.   +12 more
europepmc   +1 more source

An Lmx1a/b allelic series reveals the role of Lmx1 genes in cochlear nuclei development. [PDF]

Cell Tissue Res
Iskusnykh IY, Fritzsch B, Yamoah EN, Steshina EY, Chizhikov VV.   +4 more
europepmc   +1 more source

LMX1b is a component homeobox in the TE specification program.

We measured total transcription in the inner cell mass (ICM) and the trophectoderm (TE) of the human embryo to understand the mechanisms underlying TE commitment. We describe here discovery of Lmx1b as a lineage commitment factor in embryonic stem cells of the human embryo.
openaire   +2 more sources

Dual repression modes triggered by constitutively stabilized beta-catenin in the dorsal neural tube underlie cell fate alterations of the roof plate, neural crest, and dorsal interneurons. [PDF]

Cell Biosci
Saha SK, Zhao T, Reynolds K, McMahon M, Zhou CJ.   +4 more
europepmc   +1 more source