Results 201 to 210 of about 63,220 (230)

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

The lncrnas: innovative multifunctional players of drug resistance in colorectal cancer. [PDF]

Cancer Cell Int
Maghsoudi H, Rasoulzadeh M, Abbastabar M, Fazilat A, Sheikhnia F, Azizzadeh B, Valilo M, Majidinia M.   +7 more
europepmc   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

Animal Research and One Health, Volume 4, Issue 1, Page 14-27, February 2026.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang, Ao Guo, Lin Zhang, Shengru Wu, Juan Du, Taiyong Yu   +5 more
wiley   +1 more source

Long non-coding RNAs and therapeutic resistance in multiple myeloma: from molecular insights to clinical applications. [PDF]

Clin Exp Med
Safari MH, Farahani N, Faghih Ojaroodi A, Ebrahimpour A, Cho WC, Zare Khormizi F, Mafi A, Raesi R, Mohammad-Sadeghipour M, Alimohammadi M, Hushmandi K, Hashemi M, Taheriazam A.   +12 more
europepmc   +1 more source

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Endonuclease V: From Transcriptome Regulator to Chemical Biology Tool

ChemistryEurope, Volume 4, Issue 2, February 2026.
Post‐transcriptional modifications play a pivotal role in regulating the health and physiology of human cells, and adenosine‐to‐inosine (A‐to‐I) editing is one of the most abundant of these modifications. Inosine is read as guanosine by the cellular machinery, and this change impacts both the regulation and genetic code of RNA, in turn effectively ...
Prasanth Thota, Tyson D. Todd, Devanshi Purohit, Weina Cheng, Aastha, Jennifer M. Heemstra   +5 more
wiley   +1 more source

The role of long non-coding RNAs and circular RNAs in immune evasion of influenza A virus: recent advances. [PDF]

Front Cell Infect Microbiol
Ju Y, Li Y, Zhou C, Yu X.
europepmc   +1 more source

Transient Cyclic Structured Oligonucleotide Designs for Therapeutic Applications

Current Protocols, Volume 6, Issue 2, February 2026.
Abstract Oligonucleotide‐based therapeutics are now widely used in clinical settings. From the late 1980s to the mid‐1990s, efforts to improve therapeutic efficacy focused on imparting drug‐like properties to oligonucleotides, emphasizing nuclease stability and target sequence affinity.
Sudhir Agrawal
wiley   +1 more source

Noncoding RNAs, Vital Players in Breast Cancer Metastasis. [PDF]

Breast Cancer (Dove Med Press)
Kang Y, Wang X, Liu Y, Cao J, Lin J, Qiao G.   +5 more
europepmc   +1 more source

Epitranscriptomics as a Candidate Universal Modulator of Dormancy Transitions

Ecology and Evolution, Volume 16, Issue 2, February 2026.
Dormancy is presented as a conserved, reversible survival program in which epitranscriptomic RNA modifications are proposed to provide a rapid, energy‐efficient layer that establishes, maintains, and terminates the state by modulating mRNA stability, translation, and localization.
Ehsan Pashay Ahi
wiley   +1 more source