Results 1 to 10 of about 6,544,613 (268)

LPI-SKF: Predicting lncRNA-Protein Interactions Using Similarity Kernel Fusions [PDF]

Frontiers in Genetics, 2020
Long non-coding RNAs (lncRNAs) play an important role in serval biological activities, including transcription, splicing, translation, and some other cellular regulation processes.
Yuan-Ke Zhou, Jie Hu, Zi-Ang Shen, Wen-Ya Zhang, Pu-Feng Du   +4 more
doaj   +3 more sources

The Interaction of lncRNA-HEIH and lncRNA-HULC with HBXIP in Hepatitis B Patients

Gastroenterology Research and Practice, 2018
Hepatitis B virus (HBV) infection is a major risk factor for the development of hepatic cirrhosis (HC) and hepatocellular carcinoma (HCC), which are associated with very high morbidity and mortality rates worldwide.
Lingjuan Ruan, Lifei Huang, Lilai Zhao, Qiang Wang, Xiaocheng Pan, Anmin Zhang, Qiuping Bai, Zongjun Lv   +7 more
doaj   +2 more sources

Identification of the potential biological target molecules related to primary open-angle glaucoma

BMC Ophthalmology, 2022
Background To identify the potential biological target molecules and the corresponding interaction networks in primary open-angle glaucoma (POAG) development. Methods The microarray datasets of GSE138125 and GSE27276 concerning lncRNA and mRNA expression
Hongyu Li, Zi Ye, Zhaohui Li
doaj   +1 more source

LncRNA ENST00000532153.1 alleviates podocyte injury by inhibiting PARP1-mediated PARylation of ATF3 in diabetic kidney disease

Cellular and Molecular Life Sciences
Podocyte injury is a key event in the progression of diabetic kidney disease (DKD), and the role of long noncoding RNAs (lncRNAs) in DKD and podocyte injury is emerging.
Qun Yu, Meilin Yang, Shangwei Lu, Hong Su, Yue Liu, Xia Zhang, Xiaoting Fan, Zhimei Lv, Rong Wang   +8 more
doaj   +1 more source

Genome-wide computational analysis of potential long noncoding RNA mediated DNA:DNA:RNA triplexes in the human genome

Journal of Translational Medicine, 2017
Background Only a handful of long noncoding RNAs have been functionally characterized. They are known to modulate regulation through interacting with other biomolecules in the cell: DNA, RNA and protein.
Saakshi Jalali, Amrita Singh, Souvik Maiti, Vinod Scaria   +3 more
doaj   +1 more source

A Bipartite Network-based Method for Prediction of Long Non-coding RNA–protein Interactions

Genomics, Proteomics & Bioinformatics, 2016
As one large class of non-coding RNAs (ncRNAs), long ncRNAs (lncRNAs) have gained considerable attention in recent years. Mutations and dysfunction of lncRNAs have been implicated in human disorders.
Mengqu Ge, Ao Li, Minghui Wang
doaj   +1 more source

LncRNA CRNDE inhibits cardiomyocytes apoptosis by YAP1 in myocardial ischaemia/reperfusion injury

Autoimmunity, 2021
Background Cardiomyocytes apoptosis is the basic pathological process of myocardial ischaemia/reperfusion (MI/R) injury, so inhibiting apoptosis of cardiomyocytes can effectively improve MI/R injury.
Xiaohua Zhu, Shuiqi Li, Chen Huang, Gongcheng Huang, Jing Xu   +4 more
doaj   +1 more source

The long non-coding RNA GAS5 cooperates with the eukaryotic translation initiation factor 4E to regulate c-Myc translation. [PDF]

PLoS ONE, 2014
Long noncoding RNAs (lncRNAs) are important regulators of transcription; however, their involvement in protein translation is not well known. Here we explored whether the lncRNA GAS5 is associated with translation initiation machinery and regulates ...
Guangzhen Hu, Zhenkun Lou, Mamta Gupta
doaj   +1 more source

Long Non-Coding RNA Encoded by Infectious Bronchitis Virus Facilitates Viral Replication via Direct Interaction with G3BP2 and Expression Regulation of a Novel Host MicroRNA

Veterinary Sciences
Long non-coding RNAs (lncRNAs) encoded by viruses play crucial roles in viral infection, pathogenesis processes, the interaction between viruses and hosts, and immune escape.
Mingjing Zhang, Zhichao Cai, Hongliu An, Rong He, Songbai Zhang, Shouguo Fang   +5 more
doaj   +1 more source

Long non-coding RNA HCP5 accelerated malignant progression of ovarian cancer by inhibiting ferroptosis through interaction with polypyrimidine tract binding protein 1

Journal of Ovarian Research
Background Ovarian cancer (OVCA) is the third most common gynaecological malignancy worldwide. Long non-coding RNA (LncRNA) HCP5 and polypyrimidine tract binding protein 1 (PTBP1) involved in regulating tumors, however, with undefined mechanism in OVCA ...
Xiaoli Chen, Qing Ren, Xiaoyu Zheng, Qifeng Shen, Jian Shou   +4 more
doaj   +1 more source