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A Hybrid Prediction Method for Plant lncRNA-Protein Interaction [PDF]

open access: yesCells, 2019
Long non-protein-coding RNAs (lncRNAs) identification and analysis are pervasive in transcriptome studies due to their roles in biological processes. In particular, lncRNA-protein interaction has plausible relevance to gene expression regulation and in ...
Jael Sanyanda Wekesa   +3 more
doaj   +8 more sources

Projection-Based Neighborhood Non-Negative Matrix Factorization for lncRNA-Protein Interaction Prediction [PDF]

open access: yesFrontiers in Genetics, 2019
Many long ncRNAs (lncRNA) make their effort by interacting with the corresponding RNA-binding proteins, and identifying the interactions between lncRNAs and proteins is important to understand the functions of lncRNA. Compared with the time-consuming and
Yingjun Ma   +5 more
doaj   +6 more sources

Prediction of lncRNA–Protein Interactions via the Multiple Information Integration [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The long non-coding RNA (lncRNA)–protein interaction plays an important role in the post-transcriptional gene regulation, such as RNA splicing, translation, signaling, and the development of complex diseases.
Yifan Chen   +5 more
doaj   +5 more sources

Predicting lncRNA–Protein Interactions With miRNAs as Mediators in a Heterogeneous Network Model [PDF]

open access: yesFrontiers in Genetics, 2020
Long non-coding RNAs (lncRNAs) play important roles in various biological processes, where lncRNA–protein interactions are usually involved. Therefore, identifying lncRNA–protein interactions is of great significance to understand the molecular functions
Yuan-Ke Zhou   +5 more
doaj   +5 more sources

LPIH2V: LncRNA-protein interactions prediction using HIN2Vec based on heterogeneous networks model

open access: yesFrontiers in Genetics, 2023
LncRNA-protein interaction plays an important role in the development and treatment of many human diseases. As the experimental approaches to determine lncRNA–protein interactions are expensive and time-consuming, considering that there are few ...
Meng-Meng Wei   +8 more
doaj   +5 more sources

SGII: Systematic Identification of Essential lncRNAs in Mouse and Human Genome With lncRNA-Protein-Protein Heterogeneous Interaction Network

open access: yesFrontiers in Genetics, 2022
Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Xiao-Hong Xin   +5 more
doaj   +3 more sources

Predicting lncRNA-protein interactions with bipartite graph embedding and deep graph neural networks

open access: yesFrontiers in Genetics, 2023
Background: Long non-coding RNAs (lncRNAs) play crucial roles in numerous biological processes. Investigation of the lncRNA-protein interaction contributes to discovering the undetected molecular functions of lncRNAs.
Yuzhou Ma   +3 more
doaj   +3 more sources

LPI-KTASLP: Prediction of LncRNA-Protein Interaction by Semi-Supervised Link Learning With Multivariate Information

open access: yesIEEE Access, 2019
Long non-coding RNA, also known as lncRNA, is a series of single-stranded polynucleotides (no less than 200 nucleotides each), consisting of non-protein coding transcripts.
Cong Shen   +4 more
doaj   +3 more sources

LncRNA expression profile in human malignant embryonic rhabdomyosarcoma cell line infected with Coxsackie virus group B type 5 [PDF]

open access: yesJichu yixue yu linchuang, 2022
Objective To explore the molecular mechanism of the interaction between Coxsackie virus group B type 5 (CVB5) and the host, The long non-coding RNA(lncRNA) expression profile in human malignant embryonic rhabdomyosarcoma cell line (RD) infected by CVB5 ...
TENG Pei-ying, LI Jing, SHI Yu-lu, YANG Fan, OU Xia, CHEN Wei
doaj   +1 more source

Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation

open access: yesLife Science Alliance, 2021
The authors determined that HOTAIR specifically bind to YBX1 and promote its nuclear translocation, and then regulating cell proliferation by stimulating the PI3K/Akt and ERK/RSK signaling pathways. HOTAIR is a long noncoding RNA (lncRNA) which serves as
Siting Li   +8 more
doaj   +1 more source

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