LPI-SKF: Predicting lncRNA-Protein Interactions Using Similarity Kernel Fusions [PDF]
Frontiers in Genetics, 2020 Long non-coding RNAs (lncRNAs) play an important role in serval biological activities, including transcription, splicing, translation, and some other cellular regulation processes.
Yuan-Ke Zhou +4 more
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Long Non-Coding RNA Encoded by Infectious Bronchitis Virus Facilitates Viral Replication via Direct Interaction with G3BP2 and Expression Regulation of a Novel Host MicroRNA [PDF]
Veterinary SciencesLong non-coding RNAs (lncRNAs) encoded by viruses play crucial roles in viral infection, pathogenesis processes, the interaction between viruses and hosts, and immune escape.
Mingjing Zhang +5 more
doaj +2 more sources
Association of EEF1A1 and linc00993 expression with sperm morphology in teratozoospermia: an integrative in silico and in vitro study [PDF]
Scientific ReportsTeratozoospermia (TZ) represents a significant factor in male infertility, and for many years, evaluation of sperm morphology has been the standard diagnostic method.
Mohammadreza Saberiyan +7 more
doaj +2 more sources
A Survey of Current Resources to Study lncRNA-protein Interactions. [PDF]
Non-Coding RNA, 2021 Phenotypes are driven by regulated gene expression, which in turn are mediated by complex interactions between diverse biological molecules. Protein-DNA interactions such as histone and transcription factor binding are well studied, along with RNA-RNA interactions in short RNA silencing of genes. In contrast, lncRNA-protein interaction (LPI) mechanisms
Melcy Philip, Tyrone Chen, Sonika Tyagi
openaire +4 more sources
Protocol for detecting lncRNA-protein interactions in vitro by tRSA RNA pull-down assay
STAR ProtocolsSummary: Long non-coding RNAs (lncRNAs) work together with diverse RNA-binding proteins (RBPs) to fulfill key regulations in important cellular functions.
Liyun Jiang +4 more
doaj +3 more sources
Predicting lncRNA–Protein Interactions by Heterogenous Network Embedding [PDF]
Frontiers in Genetics, 2022 lncRNA–protein interactions play essential roles in a variety of cellular processes. However, the experimental methods for systematically mapping of lncRNA–protein interactions remain time-consuming and expensive. Therefore, it is urgent to develop reliable computational methods for predicting lncRNA–protein interactions.
Guoqing Zhao +4 more
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Function of lncRNAs and approaches to lncRNA-protein interactions [PDF]
Science China Life Sciences, 2013 Long non-coding RNAs (lncRNAs), which represent a new frontier in molecular biology, play important roles in regulating gene expression at epigenetic, transcriptional and post-transcriptional levels. More and more lncRNAs have been found to play important roles in normal cell physiological activities, and participate in the development of varieties of ...
Zhu, JuanJuan +3 more
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Integrated Bioinformatics Analysis Reveals the Impact of SHEV ORF3-Related LncRNA Network on Bile Secretion Pathway (ko 04976) in HepG2 Cells [PDF]
Veterinary Sciences(1) Background: Swine hepatitis E (SHE) is an emerging zoonotic disease caused by the swine hepatitis E virus (SHEV). The open reading frame 3 (ORF3) protein is a recognized virulence factor of SHEV.
Hanwei Jiao +7 more
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, 2022 Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Pu-Feng Du (8158638) +5 more
core +1 more source
Revealing protein-lncRNA interaction [PDF]
, 2015 Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs are often able to bind a large number of different RNAs.
Helmer Citterich, Manuela +5 more
core +1 more source