Results 41 to 50 of about 285,592 (275)

Long Noncoding RNA MEG3-205/Let-7a/MyD88 Axis Promotes Renal Inflammation and Fibrosis in Diabetic Nephropathy

open access: yesKidney Diseases, 2022
Aim: The aim of this study was to investigate the role and mechanism of long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3)-205 in renal inflammation and fibrosis in diabetic nephropathy (DN). Materials and Methods: lncRNA microarray profiling
Qimei Luo   +9 more
doaj   +1 more source

A web-based protein interaction network visualizer [PDF]

open access: yes, 2014
Background Interaction between proteins is one of the most important mechanisms in the execution of cellular functions. The study of these interactions has provided insight into the functioning of an organism’s processes.
Holifidy A Rapanoël   +11 more
core   +1 more source

Gene Ontology-based function prediction of long non-coding RNAs using bi-random walk

open access: yesBMC Medical Genomics, 2018
Background With the development of sequencing technology, more and more long non-coding RNAs (lncRNAs) have been identified. Some lncRNAs have been confirmed that they play an important role in the process of development through the dosage compensation ...
Jingpu Zhang, shuai Zou, Lei Deng
doaj   +1 more source

Prediction of protein-protein interaction types using association rule based classification

open access: yes, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Park et alBackground: Protein-protein interactions (PPI) can be classified according to their characteristics into, for example obligate or transient ...
José A Reyes   +14 more
core   +1 more source

Fitting a geometric graph to a protein-protein interaction network [PDF]

open access: yes, 2008
Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between network structure and biological function as well as into evolution.
Higham, Desmond J.   +2 more
core   +1 more source

Altered long noncoding RNA profile after intracerebral hemorrhage

open access: yesAnnals of Clinical and Translational Neurology, 2019
Objective We investigated the expression pattern of long noncoding RNAs (lncRNA) and messenger RNAs (mRNA) from two different intracerebral hemorrhage (ICH) rat models, and performed gene ontology and gene/protein interaction analyses.
Jeong‐Min Kim   +6 more
doaj   +1 more source

The binding of lncRNA RP11-732M18.3 with 14-3-3 β/α accelerates p21 degradation and promotes glioma growthResearch in context

open access: yesEBioMedicine, 2019
Background: Long noncoding RNAs (lncRNAs) have been identified as regulators of a number of developmental and tumorigenic processes. However, the functions of most lncRNAs in glioma remain unknown and the mechanisms governing the proliferation of tumor ...
Chun-Min Kang   +9 more
doaj   +1 more source

Integrated analyses of long noncoding RNAs and mRNAs in the progression of breast cancer

open access: yesJournal of International Medical Research, 2021
Objective The objective was to explore the expression and potential functions of long noncoding RNA (lncRNA) and mRNAs in human breast cancer (BC). Methods Differentially expressed lncRNAs and mRNAs were identified and annotated in BC tissues by using ...
Jingyun Guo   +6 more
doaj   +1 more source

Table_1_Projection-Based Neighborhood Non-Negative Matrix Factorization for lncRNA-Protein Interaction Prediction.xlsx

open access: yes, 2019
Many long ncRNAs (lncRNA) make their effort by interacting with the corresponding RNA-binding proteins, and identifying the interactions between lncRNAs and proteins is important to understand the functions of lncRNA. Compared with the time-consuming and
Tingting He (297525)   +2 more
core   +1 more source

Structural Modifications and Novel Protein-Binding Sites in Pre-miR-675—Explaining Its Regulatory Mechanism in Carcinogenesis

open access: yesNon-Coding RNA, 2023
Pre-miR-675 is a microRNA expressed from the exon 1 of H19 long noncoding RNA, and the atypical expression of pre-miR-675 has been linked with several diseases and disorders including cancer. To execute its function inside the cell, pre-miR-675 is folded
Abhishek Dey
doaj   +1 more source

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