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, 2022 Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Pu-Feng Du (8158638) +5 more
core +1 more source
Probing lncRNA–Protein Interactions: Data Repositories, Models, and Algorithms
Frontiers in Genetics, 2020 Identifying lncRNA-protein interactions (LPIs) is vital to understanding various key biological processes. Wet experiments found a few LPIs, but experimental methods are costly and time-consuming. Therefore, computational methods are increasingly exploited to capture LPI candidates.
Lihong Peng +8 more
openaire +3 more sources
LPI-CSFFR: Combining Serial Fusion with Feature Reuse for Predicting LncRNA-Protein Interactions [PDF]
Computational Biology and Chemistry, 2022 <p>Long non-coding RNAs (LncRNAs) play important roles in a series of life activities, and they function primarily with proteins. The wet experimental-based methods in lncRNA-protein interactions (lncRPIs) study are time-consuming. Therefore, in this study, we propose a reliable computational-based method called LPI-CSFFR using sequences ...
Xiaoqian Huang +5 more
openaire +2 more sources
, 2022 Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Pu-Feng Du (8158638) +5 more
core +1 more source
Molecular Therapy: Nucleic Acids, 2018 With the development of science and biotechnology, many evidences show that ncRNAs play an important role in the development of important biological processes, especially in chromatin modification, cell differentiation and proliferation, RNA progressing,
Qi Zhao +5 more
doaj +1 more source
Frontiers in Integrative Neuroscience, 2021 Objective: This study aimed to investigate the possible molecular mechanisms associated with ischemic stroke through the construction of a lncRNA-miRNA-mRNA network.
Yaxuan Sun +5 more
doaj +1 more source
BMC Endocrine Disorders, 2022 Objective The incidence of papillary thyroid cancer (PTC) concomitant with Hashimoto’s thyroiditis (HT) is gradually increasing over the past decades.
Yuepeng Zhang, Yueli Tian
doaj +1 more source
Evolutionarily conserved herpesviral protein interaction networks. [PDF]
, 2009 Herpesviruses constitute a family of large DNA viruses widely spread in vertebrates and causing a variety of different diseases. They possess dsDNA genomes ranging from 120 to 240 kbp encoding between 70 to 170 open reading frames. We previously reported
Bandyopadhyay, Sourav +79 more
core +1 more source
Genome Biology, 2023 Background Extensive studies have revealed the function and mechanism of lncRNAs in development and differentiation, but the majority have focused on those lncRNAs adjacent to protein-coding genes.
Pei Lu +9 more
doaj +1 more source
HLPI-Ensemble: Prediction of human lncRNA-protein interactions based on ensemble strategy [PDF]
RNA Biology, 2018 LncRNA plays an important role in many biological and disease progression by binding to related proteins. However, the experimental methods for studying lncRNA-protein interactions are time-consuming and expensive. Although there are a few models designed to predict the interactions of ncRNA-protein, they all have some common drawbacks that limit their
Huan Hu +6 more
openaire +2 more sources