Results 81 to 90 of about 39,808 (145)
, 2015 Background/Aims: Non-coding RNAs including miRNA and lncRNA had been reported to regulate gene expression and were both related to cancer progression.
Ge Yue +5 more
core +1 more source
Genomic imprinting defects in the growth disorder Beckwith-Wiedemann syndrome [PDF]
, 2009 The imprinting control region (IC1) of the human IGF2 and H19 genes is represented by a chromatin insulator located between the two genes that prevents the activation of IGF2 and allows the activation of H19 on the maternal chromosome. Deletions removing
Citro, Valentina
core +1 more source
LncRNA H19-elevated LIN28B promotes lung cancer progression through sequestering miR-196b
, 2018 LncRNA H19 is involved in the development of multiple cancers. Here, we firstly provide new evidence that H19 can induce LIN28B, a conserved RNA binding protein, to accelerate lung cancer growth through sponging miR-196b. Abundance in LIN28B was observed
Rong Gao (476219) +6 more
core +1 more source
Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours
Nature Communications, 2018 LncRNA H19 has been shown to be aberrantly expressed in different cancers. Here, the authors show that H19 lncRNA is downregulated in pituitary adenomas and H19 is able to impede pituitary tumorigenesis via disruption of 4E-BPB1 and Raptor interaction to
Ze Rui Wu +18 more
doaj +1 more source
Objective: Nodular goiter may increase the risk of thyroid cancer, but the genetic factors contributing to nodular goiter are not well understood. There is an overexpression of H19 lncRNA in goiter tissue and its target remains unknown. In this study, we
Seyed-Morteza Javadirad
core +1 more source
Levonorgestrel Ameliorates Adenomyosis via lncRNA H19/miR-17/TLR4 Pathway
Drug Design, Development and Therapy, 2020 Na Liang,1,* Wenfeng Zhang,2,* Hongjiang Wang,3 Wei Shi,4 Li Wang,2 Lijuan Ma2 1Department of Traditional Chinese Medicine, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Shandong University ...
Liang N +5 more
doaj
H19 lncRNA regulates keratinocyte differentiation by targeting miR-130b-3p
, 2017 Aberrant differentiation of keratinocytes has been demonstrated to be associated with a number of skin diseases. A growing number of studies have showed that long noncoding RNAs (lncRNAs) have an important part in gene regulation, however, the role of ...
Zhi-rong Yao +7 more
core +1 more source
Journal of Tissue EngineeringEndothelial injury is a key factor initiating in-stent restenosis (ISR) following peripheral artery stent implantation. Genetically modified endothelial progenitor cells (EPCs) can promote reendothelialization of injured arteries and inhibit neointimal ...
Yanchen Ye +9 more
doaj +1 more source
, 2018 Background Astrocyte and microglia activation are well-known features of temporal lobe epilepsy that may contribute to epileptogenesis. However, the mechanisms underlying glia activation are not well understood.
Yun-Peng Liu +10 more
core +1 more source
LncRNA H19 drives atherosclerosis progression via the miR-let-7a/ITGB3 axis. [PDF]
Front PhysiolHu ZY +11 more
europepmc +1 more source