Results 1 to 10 of about 1,823,262 (282)

Modelling Competing Endogenous RNA Networks. [PDF]

PLoS ONE, 2013
MicroRNAs (miRNAs) are small RNA molecules, about 22 nucleotide long, which post-transcriptionally regulate their target messenger RNAs (mRNAs).
Carla Bosia, Andrea Pagnani, Riccardo Zecchina   +2 more
doaj   +10 more sources

Noncoding RNA-associated competing endogenous RNA networks in trastuzumab-induced cardiotoxicity [PDF]

Non-coding RNA Research
Trastuzumab-induced cardiotoxicity (TIC) is a common and serious disease with abnormal cardiac function. Accumulating evidence has indicated certain non-coding RNAs (ncRNAs), functioning as competing endogenous RNAs (ceRNAs), impacting the progression of
Suifen Xie, Ni Zhou, Nan Su, Zijun Xiao, Shanshan Wei, Yuanying Yang, Jian Liu, Wenqun Li, Bikui Zhang   +8 more
doaj   +6 more sources

circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA [PDF]

eLife, 2023
Circular RNAs represent a class of endogenous RNAs that regulate gene expression and influence cell biological decisions with implications for the pathogenesis of several diseases.
Trine Line Hauge Okholm, Andreas Bjerregaard Kamstrup, Morten Muhlig Nielsen, Anne Kruse Hollensen, Mette Laugesen Graversgaard, Matilde Helbo Sørensen, Lasse Sommer Kristensen, Søren Vang, Samuel S Park, Eugene Yeo, Lars Dyrskjøt, Jørgen Kjems, Jakob Skou Pedersen, Christian Kroun Damgaard   +13 more
doaj   +7 more sources

Revealing Landscape of Competing Endogenous RNA Networks in Sepsis-Induced Cardiovascular Diseases [PDF]

Reviews in Cardiovascular Medicine, 2023
Cardiovascular dysfunction induced by sepsis is one of the most common phenotypes of cardiovascular diseases (CVDs), which is closely related to the high mortality of sepsis and is an urgent health problem to be solved worldwide. Unfortunately, the exact
Wei Xiong, Shiyan Feng, Yanhua Zhao, Xinquan Liu, Jian Gong   +4 more
doaj   +3 more sources

Competing Endogenous RNA Networks in Glioma [PDF]

Frontiers in Genetics, 2021
Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high ...
Liang Cen, Liang Cen, Ruochen Liu, Ruochen Liu, Wei Liu, Wei Liu, Qianqian Li, Hongjuan Cui, Hongjuan Cui, Hongjuan Cui   +9 more
doaj   +3 more sources

Competing endogenous RNA networks in ovarian cancer [PDF]

EXCLI Journal : Experimental and Clinical Sciences
Epithelial ovarian cancer is responsible for the majority of ovarian malignancies, and its highly invasive nature and chemoresistant development have been major obstacles to treating patients with mainstream treatments.
Roghaiyeh Derogar, Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +2 more
doaj   +2 more sources

LUCAT1-Mediated Competing Endogenous RNA (ceRNA) Network in Triple-Negative Breast Cancer [PDF]

Cells
Breast cancer is a heterogeneous disease comprising multiple molecularly distinct subtypes with varied prevalence, prognostics, and treatment strategies.
Deepak Verma, Sumit Siddharth, Ashutosh S. Yende, Qitong Wu, Dipali Sharma   +4 more
doaj   +2 more sources

EZH2: A Crucial Competing Endogenous RNA in Cancer Research-A Scoping Review [PDF]

Advanced Biomedical Research
Recently, research on the competing endogenous RNAs (ceRNAs) in cancer has been in full swing, emphasizing their importance as critical RNAs in cancer progression.
Sadra Salehi-Mazandarani, Sharareh Mahmoudian-Hamedani, Ziba Farajzadegan, Parvaneh Nikpour   +3 more
doaj   +2 more sources

Competing endogenous RNA networks and ferroptosis in cancer: novel therapeutic targets [PDF]

Cell Death and Disease
As a newly identified regulated cell death, ferroptosis is a metabolically driven process that relies on iron and is associated with polyunsaturated fatty acyl peroxidation, elevated levels of reactive oxygen species (ROS), and mitochondrial damage. This
Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +1 more
doaj   +2 more sources

A novel ceRNA-immunoregulatory axis based on immune cell infiltration in ulcerative colitis-associated colorectal carcinoma by integrated weighted gene co-expression network analysis

BMC Gastroenterology, 2022
Background Patients with ulcerative colitis are at an increased risk of developing colorectal cancer with a prolonged disease course. Many studies have shown that alterations in the immune microenvironment play a key role in ulcerative colitis-associated
Shi Yin, Xianzhe Li, Zhizhong Xiong, Minghao Xie, Longyang Jin, Huaxian Chen, Chaobin Mao, Fengxiang Zhang, Lei Lian   +8 more
doaj   +1 more source