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Noncoding RNA-associated competing endogenous RNA networks in trastuzumab-induced cardiotoxicity [PDF]

open access: yesNon-coding RNA Research
Trastuzumab-induced cardiotoxicity (TIC) is a common and serious disease with abnormal cardiac function. Accumulating evidence has indicated certain non-coding RNAs (ncRNAs), functioning as competing endogenous RNAs (ceRNAs), impacting the progression of
Suifen Xie   +8 more
doaj   +4 more sources

circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA [PDF]

open access: yeseLife, 2023
Circular RNAs represent a class of endogenous RNAs that regulate gene expression and influence cell biological decisions with implications for the pathogenesis of several diseases.
Trine Line Hauge Okholm   +13 more
doaj   +7 more sources

Competing Endogenous RNA Networks in Glioma [PDF]

open access: yesFrontiers in Genetics, 2021
Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high ...
Liang Cen   +9 more
doaj   +3 more sources

Modelling Competing Endogenous RNA Networks. [PDF]

open access: yesPLoS ONE, 2013
MicroRNAs (miRNAs) are small RNA molecules, about 22 nucleotide long, which post-transcriptionally regulate their target messenger RNAs (mRNAs).
Carla Bosia   +2 more
doaj   +6 more sources

Competing endogenous RNA networks in ovarian cancer [PDF]

open access: yesEXCLI Journal : Experimental and Clinical Sciences
Epithelial ovarian cancer is responsible for the majority of ovarian malignancies, and its highly invasive nature and chemoresistant development have been major obstacles to treating patients with mainstream treatments.
Roghaiyeh Derogar   +2 more
doaj   +2 more sources

Revealing Landscape of Competing Endogenous RNA Networks in Sepsis-Induced Cardiovascular Diseases [PDF]

open access: yesReviews in Cardiovascular Medicine, 2023
Cardiovascular dysfunction induced by sepsis is one of the most common phenotypes of cardiovascular diseases (CVDs), which is closely related to the high mortality of sepsis and is an urgent health problem to be solved worldwide. Unfortunately, the exact
Wei Xiong   +4 more
doaj   +2 more sources

LUCAT1-Mediated Competing Endogenous RNA (ceRNA) Network in Triple-Negative Breast Cancer [PDF]

open access: yesCells
Breast cancer is a heterogeneous disease comprising multiple molecularly distinct subtypes with varied prevalence, prognostics, and treatment strategies.
Deepak Verma   +4 more
doaj   +2 more sources

EZH2: A Crucial Competing Endogenous RNA in Cancer Research-A Scoping Review [PDF]

open access: yesAdvanced Biomedical Research
Recently, research on the competing endogenous RNAs (ceRNAs) in cancer has been in full swing, emphasizing their importance as critical RNAs in cancer progression.
Sadra Salehi-Mazandarani   +3 more
doaj   +2 more sources

Competing endogenous RNA networks and ferroptosis in cancer: novel therapeutic targets [PDF]

open access: yesCell Death and Disease
As a newly identified regulated cell death, ferroptosis is a metabolically driven process that relies on iron and is associated with polyunsaturated fatty acyl peroxidation, elevated levels of reactive oxygen species (ROS), and mitochondrial damage. This
Fatemeh Nejadi Orang   +1 more
doaj   +2 more sources

A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene Expression in GnRH Neuronal Cell Models. [PDF]

open access: yes, 2016
Gonadotropin-releasing hormone (GnRH), a neuropeptide released from a small population of neurons in the hypothalamus, is the central mediator of the hypothalamic-pituitary-gonadal axis, and is required for normal reproductive development and function ...
Brusman, Liza E   +4 more
core   +24 more sources

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