Results 1 to 10 of about 299,250 (314)

Noncoding RNA-associated competing endogenous RNA networks in trastuzumab-induced cardiotoxicity [PDF]

Non-coding RNA Research
Trastuzumab-induced cardiotoxicity (TIC) is a common and serious disease with abnormal cardiac function. Accumulating evidence has indicated certain non-coding RNAs (ncRNAs), functioning as competing endogenous RNAs (ceRNAs), impacting the progression of
Suifen Xie, Ni Zhou, Nan Su, Zijun Xiao, Shanshan Wei, Yuanying Yang, Jian Liu, Wenqun Li, Bikui Zhang   +8 more
doaj   +8 more sources

circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA [PDF]

eLife, 2023
Circular RNAs represent a class of endogenous RNAs that regulate gene expression and influence cell biological decisions with implications for the pathogenesis of several diseases.
Trine Line Hauge Okholm, Andreas Bjerregaard Kamstrup, Morten Muhlig Nielsen, Anne Kruse Hollensen, Mette Laugesen Graversgaard, Matilde Helbo Sørensen, Lasse Sommer Kristensen, Søren Vang, Samuel S Park, Eugene Yeo, Lars Dyrskjøt, Jørgen Kjems, Jakob Skou Pedersen, Christian Kroun Damgaard   +13 more
doaj   +8 more sources

Competing Endogenous RNA Networks as Biomarkers in Neurodegenerative Diseases [PDF]

International Journal of Molecular Sciences, 2020
Protein aggregation is classically considered the main cause of neuronal death in neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration of RNA metabolism is a key factor in the etiopathogenesis of these complex ...
Ana Calvo, Rosario Osta, Janne M Toivonen   +2 more
exaly   +8 more sources

A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA [PDF]

Cell, 2011
Summary Recently, a new regulatory circuitry has been identified in which RNAs can crosstalk with each other by competing for shared microRNAs. Such competing endogenous RNAs (ceRNAs) regulate the distribution of miRNA molecules on their targets and ...
Irène Bozzoni, Mauro Chinappi, Anna Tramontano   +2 more
exaly   +12 more sources

Competing Endogenous RNA Networks in Glioma [PDF]

Frontiers in Genetics, 2021
Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high ...
Liang Cen, Liang Cen, Ruochen Liu, Ruochen Liu, Wei Liu, Wei Liu, Qianqian Li, Hongjuan Cui, Hongjuan Cui, Hongjuan Cui   +9 more
doaj   +4 more sources

Competing endogenous RNA networks and ferroptosis in cancer: novel therapeutic targets [PDF]

Cell Death and Disease
As a newly identified regulated cell death, ferroptosis is a metabolically driven process that relies on iron and is associated with polyunsaturated fatty acyl peroxidation, elevated levels of reactive oxygen species (ROS), and mitochondrial damage. This
Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +1 more
doaj   +3 more sources

Role of circular RNA as competing endogenous RNA in ovarian cancer (Review). [PDF]

Int J Mol Med
Circular RNA (circRNA), a type of non-coding RNA, plays a regulatory role in biological processes. The special loop structure of circRNA makes it highly stable and specific in diseased tissues and cells, especially in tumors.
Ye W, Xiang N, Wang Q, Lu Y.
europepmc   +4 more sources

Biomarker potential of competing endogenous RNA networks in Polycystic Ovary Syndrome (PCOS). [PDF]

Noncoding RNA Res
Polycystic ovary syndrome (PCOS) is the most common condition affecting women of reproductive age globally. PCOS continues to be the largest contributing factor to female infertility despite significant progress in our knowledge of the molecular ...
Heidarzadehpilehrood R, Pirhoushiaran M.
europepmc   +4 more sources

Competing endogenous RNA networks in ovarian cancer [PDF]

EXCLI Journal : Experimental and Clinical Sciences
Epithelial ovarian cancer is responsible for the majority of ovarian malignancies, and its highly invasive nature and chemoresistant development have been major obstacles to treating patients with mainstream treatments.
Roghaiyeh Derogar, Fatemeh Nejadi Orang, Mahdi Abdoli Shadbad   +2 more
doaj   +2 more sources

The role of competing endogenous RNA network in the development of hepatocellular carcinoma: potential therapeutic targets. [PDF]

Front Cell Dev Biol
The current situation of hepatocellular carcinoma (HCC) management is challenging due to its high incidence, mortality, recurrence and metastasis. Recent advances in gene genetic and expression regulation have unveiled the significant role of non-coding ...
Tang Z, Li X, Zheng Y, Liu J, Liu C, Li X.   +5 more
europepmc   +2 more sources