Modelling Competing Endogenous RNA Networks. [PDF]
PLoS ONE, 2013 MicroRNAs (miRNAs) are small RNA molecules, about 22 nucleotide long, which post-transcriptionally regulate their target messenger RNAs (mRNAs).
Carla Bosia +2 more
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Noncoding RNA-associated competing endogenous RNA networks in trastuzumab-induced cardiotoxicity [PDF]
Non-coding RNA ResearchTrastuzumab-induced cardiotoxicity (TIC) is a common and serious disease with abnormal cardiac function. Accumulating evidence has indicated certain non-coding RNAs (ncRNAs), functioning as competing endogenous RNAs (ceRNAs), impacting the progression of
Suifen Xie +8 more
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Competing endogenous RNA crosstalk at system level. [PDF]
PLoS Computational Biology, 2019 microRNAs (miRNAs) regulate gene expression at post-transcriptional level by repressing target RNA molecules. Competition to bind miRNAs tends in turn to correlate their targets, establishing effective RNA-RNA interactions that can influence expression ...
Mattia Miotto +2 more
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Competing Endogenous RNA: The Key to Posttranscriptional Regulation [PDF]
The Scientific World Journal, 2014 Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA.
Rituparno Sen +4 more
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Competing Endogenous RNA Networks as Biomarkers in Neurodegenerative Diseases [PDF]
International Journal of Molecular Sciences, 2020 Protein aggregation is classically considered the main cause of neuronal death in neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration of RNA metabolism is a key factor in the etiopathogenesis of these complex ...
Leticia Moreno-García +2 more
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circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA [PDF]
eLife, 2023 Circular RNAs represent a class of endogenous RNAs that regulate gene expression and influence cell biological decisions with implications for the pathogenesis of several diseases.
Trine Line Hauge Okholm +13 more
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Revealing Landscape of Competing Endogenous RNA Networks in Sepsis-Induced Cardiovascular Diseases [PDF]
Reviews in Cardiovascular Medicine, 2023 Cardiovascular dysfunction induced by sepsis is one of the most common phenotypes of cardiovascular diseases (CVDs), which is closely related to the high mortality of sepsis and is an urgent health problem to be solved worldwide. Unfortunately, the exact
Wei Xiong +4 more
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A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA [PDF]
Cell, 2011 Recently, a new regulatory circuitry has been identified in which RNAs can crosstalk with each other by competing for shared microRNAs. Such competing endogenous RNAs (ceRNAs) regulate the distribution of miRNA molecules on their targets and thereby ...
Marcella Cesana +2 more
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Competing Endogenous RNA Networks in Glioma [PDF]
Frontiers in Genetics, 2021 Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high ...
Liang Cen +9 more
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Competing endogenous RNA networks in ovarian cancer [PDF]
EXCLI Journal : Experimental and Clinical SciencesEpithelial ovarian cancer is responsible for the majority of ovarian malignancies, and its highly invasive nature and chemoresistant development have been major obstacles to treating patients with mainstream treatments.
Roghaiyeh Derogar +2 more
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