Results 21 to 30 of about 312,740 (284)

A novel ceRNA-immunoregulatory axis based on immune cell infiltration in ulcerative colitis-associated colorectal carcinoma by integrated weighted gene co-expression network analysis

open access: yesBMC Gastroenterology, 2022
Background Patients with ulcerative colitis are at an increased risk of developing colorectal cancer with a prolonged disease course. Many studies have shown that alterations in the immune microenvironment play a key role in ulcerative colitis-associated
Shi Yin   +8 more
doaj   +1 more source

Integrated analysis of competing endogenous RNA in esophageal carcinoma [PDF]

open access: yesJournal of Gastrointestinal Oncology, 2021
The Competing endogenous RNA (CeRNA) network plays important roles in the development and progression of multiple human cancers. Increasing attention has been paid to CeRNA in esophageal carcinoma (ESCA).We explored The Cancer Genome Atlas (TCGA) database and then analyzed the RNAs of 142 samples to obtain long non-coding RNAs (lncRNAs), micro RNAs ...
Nanzheng, Chen   +5 more
openaire   +2 more sources

PVT1: a rising star among oncogenic long non-coding RNAs [PDF]

open access: yes, 2015
It is becoming increasingly clear that short and long noncoding RNAs critically participate in the regulation of cell growth, differentiation, and (mis)function.
Colombo, Teresa   +3 more
core   +9 more sources

Construction of asthma related competing endogenous RNA network revealed novel long non-coding RNAs and potential new drugs

open access: yesRespiratory Research, 2020
Background Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases.
Yifang Liao   +5 more
doaj   +1 more source

The emerging roles of non-coding competing endogenous RNA in hepatocellular carcinoma

open access: yesCancer Cell International, 2020
Accumulating evidence has emerged revealing that noncoding RNAs (ncRNAs) play essential roles in the occurrence and development of hepatocellular carcinoma (HCC). However, the complicated regulatory interactions among various ncRNAs in the development of
Gang Xu   +6 more
doaj   +1 more source

A Novel Immune-Related Competing Endogenous RNA Network Predicts Prognosis of Acute Myeloid Leukemia

open access: yesFrontiers in Oncology, 2020
BackgroundAcute myeloid leukemia (AML) is a genetically, biologically and clinically heterogeneous hematopoietic malignancy that is highly dependent on the bone marrow (BM) microenvironment.
Shujuan Wang   +7 more
doaj   +1 more source

MiR-96 induced non-small-cell lung cancer progression through competing endogenous RNA network and affecting EGFR signaling pathway [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2019
Objective(s): Non-small cell lung cancer (NSCLC) has become a serious global health problem in the 21st century, and tumor proliferation and metastasis are the leading causes of death in patients  with lung cancer.
Hao Ding   +5 more
doaj   +1 more source

Roles of competing endogenous RNAs in gastric cancer [PDF]

open access: yesBriefings in Functional Genomics, 2015
Long noncoding RNA (lncRNA) is >200 nucleotides long and lacks coding ability. LncRNA was regarded as transcript noise, until emerging results showed its roles in development, homeostasis and carcinogenesis. LncRNAs containing microRNA (miRNA) response elements could compete with the miRNA target gene and regulate its expression through decreasing free
Ye, Hu   +3 more
openaire   +2 more sources

Regulatory Potential of Competing Endogenous RNAs in Myotonic Dystrophies [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Non-coding RNAs (ncRNAs) have been reported to be implicated in cell fate determination and various human diseases. All ncRNA molecules are emerging as key regulators of diverse cellular processes; however, little is known about the regulatory interaction among these various classes of RNAs.
Edyta Koscianska   +2 more
openaire   +2 more sources

Comprehensive circRNA-microRNA-mRNA network analysis revealed the novel regulatory mechanism of Trichosporon asahii infection

open access: yesMilitary Medical Research, 2021
Background Invasive Trichosporon asahii (T. asahii) infection frequently occurs with a high mortality in immunodeficient hosts, but the pathogenesis of T. asahii infection remains elusive.
Ming-Wang Zhang   +6 more
doaj   +1 more source

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