Results 21 to 30 of about 238,324 (282)
Biomarker potential of competing endogenous RNA networks in Polycystic Ovary Syndrome (PCOS). [PDF]
Noncoding RNA ResPolycystic ovary syndrome (PCOS) is the most common condition affecting women of reproductive age globally. PCOS continues to be the largest contributing factor to female infertility despite significant progress in our knowledge of the molecular ...
Heidarzadehpilehrood R, Pirhoushiaran M.
europepmc +2 more sources
Constructing a competing endogenous RNA network for osteoarthritis [PDF]
Annals of Translational Medicine, 2022 Osteoarthritis (OA) is one of the most common diseases in elderly people; however, the correlation between molecular alterations and the occurrence and progression of OA are still not well understood. We conducted this study to investigate the molecular changes in OA via the competing endogenous ribonucleic acid (ceRNA) network.We downloaded the ...
Hua, Shu-Liang +5 more
openaire +2 more sources
Competing endogenous RNAs in lung cancer
Cancer Biology and Medicine, 2021 Competing endogenous RNAs (ceRNAs) containing microRNA response elements can competitively interact with microRNA via miRNA response elements, which can combine non-coding RNAs with protein-coding RNAs through complex ceRNA networks. CeRNAs include non-coding RNAs (long non-coding RNAs, circular RNAs, and transcribed pseudogenes) and protein-coding ...
Meilian Zhao, Jianguo Feng, Liling Tang
openaire +4 more sources
Competing endogenous RNA database [PDF]
Bioinformation, 2012 A given mRNA can be regulated by interactions with miRNAs and in turn the availability of these miRNAs can be regulated by their interactions with alternate mRNAs. The concept of regulation of a given mRNA by alternate mRNA (competing endogenous mRNA) by virtue of interactions with miRNAs through shared miRNA response elements is poised to become a ...
Sarver, Aaron L, Subramanian, Subbaya
openaire +2 more sources
BMC Gastroenterology, 2022 Background Patients with ulcerative colitis are at an increased risk of developing colorectal cancer with a prolonged disease course. Many studies have shown that alterations in the immune microenvironment play a key role in ulcerative colitis-associated
Shi Yin +8 more
doaj +1 more source
Regulatory Potential of Competing Endogenous RNAs in Myotonic Dystrophies [PDF]
International Journal of Molecular Sciences, 2021 Non-coding RNAs (ncRNAs) have been reported to be implicated in cell fate determination and various human diseases. All ncRNA molecules are emerging as key regulators of diverse cellular processes; however, little is known about the regulatory interaction among these various classes of RNAs.
Edyta Koscianska +2 more
openaire +2 more sources
Competing endogenous RNA network for esophageal cancer progression [PDF]
Annals of Translational Medicine, 2021 Esophageal cancer (ESCA) constitutes one of the most common cancers worldwide. The identification of potential biomarkers is important to improving the diagnostic accuracy and treatment efficiency for patients with ESCA. In this study, we aimed to identify biomarkers related to ESCA progression through a comprehensive analysis of long non-coding RNAs ...
Chen, Saihua +9 more
openaire +2 more sources
Integrated analysis of competing endogenous RNA in esophageal carcinoma [PDF]
Journal of Gastrointestinal Oncology, 2021 The Competing endogenous RNA (CeRNA) network plays important roles in the development and progression of multiple human cancers. Increasing attention has been paid to CeRNA in esophageal carcinoma (ESCA).We explored The Cancer Genome Atlas (TCGA) database and then analyzed the RNAs of 142 samples to obtain long non-coding RNAs (lncRNAs), micro RNAs ...
Nanzheng, Chen +5 more
openaire +2 more sources
Roles of competing endogenous RNAs in gastric cancer [PDF]
Briefings in Functional Genomics, 2015 Long noncoding RNA (lncRNA) is >200 nucleotides long and lacks coding ability. LncRNA was regarded as transcript noise, until emerging results showed its roles in development, homeostasis and carcinogenesis. LncRNAs containing microRNA (miRNA) response elements could compete with the miRNA target gene and regulate its expression through decreasing free
Ye, Hu +3 more
openaire +2 more sources
Long Noncoding Competing Endogenous RNA Networks in Pancreatic Cancer
Frontiers in Oncology, 2021 Pancreatic cancer (PC) is a highly malignant disease characterized by insidious onset, rapid progress, and poor therapeutic effects. The molecular mechanisms associated with PC initiation and progression are largely insufficient, hampering the ...
Guangbing Xiong +10 more
doaj +1 more source