Results 41 to 50 of about 238,324 (282)

Analyzing the lncRNA, miRNA, and mRNA-associated ceRNA networks to reveal potential prognostic biomarkers for glioblastoma multiforme

Cancer Cell International, 2020
Background Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNAs) act as microRNA (miRNA) sponges
Xiaolong Zhu, Lan Jiang, Hui Yang, Tianbing Chen, Xingwei Wu, Kun Lv   +5 more
doaj   +1 more source

KCNQ1OT1: An Oncogenic Long Noncoding RNA

Biomolecules, 2021
Long noncoding RNAs (lncRNAs) are transcripts greater than 200 nucleotides that do not code for proteins but regulate gene expression. Recent studies indicate that lncRNAs are involved in the modulation of biological functions in human disease.
Patrice Cagle, Qi Qi, Suryakant Niture, Deepak Kumar   +3 more
doaj   +1 more source

Integral Analyses of Competing Endogenous RNA Mechanisms and DNA Methylation Reveal Regulatory Mechanisms in Osteosarcoma

Frontiers in Cell and Developmental Biology, 2021
Background: Osteosarcoma (OS) is the most common primary malignant bone tumour in children and adolescents, with rapid growth, frequent metastasis, and a poor prognosis, but its pathogenesis has not been fully elucidated. Exploring the pathogenesis of OS
Tingrui Wu, Bo Wei, Hao Lin, Boan Zhou, Tao Lin, Qianzheng Liu, Hongxun Sang, Huan Liu, Huan Liu, Wenhua Huang, Wenhua Huang, Wenhua Huang   +11 more
doaj   +1 more source

Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Hepatocellular carcinoma (HCC) is a common and lethal type of cancer worldwide. The importance of non-coding RNAs such as long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs) have been recognized in the ...
Mohammad Donyavi, Sadra Salehi-Mazandarani, Parvaneh Nikpour   +2 more
doaj   +1 more source

Circular RNAs and competing endogenous RNA (ceRNA) networks

Translational Cancer Research, 2018
In recent years, advances in bioinformatics approaches have allowed a systematic characterization of circular RNAs (circRNAs) across a variety of cell types. Demonstration of cell type specificity, regulated expression, and conservation between species all suggest that circRNAs have functional importance.
Apratim, Mitra, Karl, Pfeifer, Ki-Sun, Park   +2 more
openaire   +2 more sources

CircPlekha7 plays an anti-fibrotic role in intrauterine adhesions by modulating endometrial stromal cell proliferation and apoptosis

The Journal of Reproduction and Development, 2020
Circular RNA (circRNA) plays a key role in the development and progression of several diseases; however, its role in intrauterine adhesions (IUAs) is not well understood.
Wei XIE, Min HE, Yuhuan LIU, Xiaowu HUANG, Dongmei SONG, Yu XIAO   +5 more
doaj   +1 more source

The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia

BMC Cancer, 2021
Background As one of the novel molecules, circRNA has been identified closely involved in the pathogenesis of many diseases. However, the function of circRNA in acute myeloid leukemia (AML) still remains unknown.
Siyuan Zhang
doaj   +1 more source

Flavonoids Inhibit Cancer by Regulating the Competing Endogenous RNA Network

Frontiers in Oncology, 2022
Flavonoids are present in a wide range of plants. They have been used in the treatment of cancer, but the mechanism underlying this activity is unclear.
Chengshun Li, Xiaolan Li, Ziping Jiang, Dongxu Wang, Liqun Sun, Jiaqi Li, Yang Han   +6 more
doaj   +1 more source

Competing endogenous RNA networks and gastric cancer

World Journal of Gastroenterology, 2015
Recent studies have showed that RNAs regulate each other with microRNA (miRNA) response elements (MREs) and this mechanism is known as "competing endogenous RNA (ceRNA)" hypothesis. Long non-coding RNAs (lncRNAs) are supposed to play important roles in cancer.
Lei-Lei, Guo, Chun-Hua, Song, Peng, Wang, Li-Ping, Dai, Jian-Ying, Zhang, Kai-Juan, Wang   +5 more
openaire   +2 more sources

The top 15 nodes in the competing endogenous RNA (ceRNA) regulatory network in the blue module and the turquoise module.

, 2022
The top 15 nodes in the competing endogenous RNA (ceRNA) regulatory network in the blue module and the turquoise module.
Ren-Dong Xiao (12878506), Yu Wang (12152), Quan Du (58889), Rong-Gang Luo (12878509), Jin-Bao Xie (12878512), Zu-Dong Su (12878515)   +5 more
core   +1 more source