Results 41 to 50 of about 312,740 (284)
The Journal of Reproduction and Development, 2020 Circular RNA (circRNA) plays a key role in the development and progression of several diseases; however, its role in intrauterine adhesions (IUAs) is not well understood.
Wei XIE +5 more
doaj +1 more source
The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia
BMC Cancer, 2021 Background As one of the novel molecules, circRNA has been identified closely involved in the pathogenesis of many diseases. However, the function of circRNA in acute myeloid leukemia (AML) still remains unknown.
Siyuan Zhang
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Background: Osteosarcoma (OS) is the most common primary malignant bone tumour in children and adolescents, with rapid growth, frequent metastasis, and a poor prognosis, but its pathogenesis has not been fully elucidated. Exploring the pathogenesis of OS
Tingrui Wu +11 more
doaj +1 more source
Interaction and cross-talk between non-coding RNAs. [PDF]
, 2017 Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a competing endogenous RNAs (ceRNAs) where microRNAs (miRNAs) and lncRNAs regulate each ...
Dahiya, Rajvir +3 more
core +2 more sources
Competing endogenous RNA networks and gastric cancer
World Journal of Gastroenterology, 2015 Recent studies have showed that RNAs regulate each other with microRNA (miRNA) response elements (MREs) and this mechanism is known as "competing endogenous RNA (ceRNA)" hypothesis. Long non-coding RNAs (lncRNAs) are supposed to play important roles in cancer.
Lei-Lei, Guo +5 more
openaire +2 more sources
Rocaglates induce gain-of-function alterations to eIF4A and eIF4F [PDF]
, 2020 Rocaglates are a diverse family of biologically active molecules that have gained tremendous interest in recent years due to their promising activities in pre-clinical cancer studies.
Baranov, Pavel V. +12 more
core +1 more source
Differently Expressed Circular RNAs in Lacrimal Sacs From Patients With Chronic Dacryocystitis
Frontiers in Genetics, 2022 This study was designed to identify differently expressed circular RNAs (circRNAs) and investigate their potential roles in lacrimal sacs from patients with chronic dacryocystitis.
Yue Li +11 more
doaj +1 more source
Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion [PDF]
, 2017 Thousands of genes have been well demonstrated to play important roles in cancer progression. As genes do not function in isolation, they can be grouped into “networks” based on their interactions.
Chen, Xiao-wan +9 more
core +2 more sources
Long Non-Coding RNA- Associated Competing Endogenous RNA Axes in T-Cells in Multiple Sclerosis
Frontiers in Immunology, 2021 Multiple sclerosis (MS) is an immune-mediated demyelinating and degenerative disease with unknown etiology. Inappropriate response of T-cells to myelin antigens has an essential role in the pathophysiology of MS.
Hani Sabaie +11 more
doaj +1 more source
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]
, 2010 Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud +7 more
core +1 more source