Circular RNAs and competing endogenous RNA (ceRNA) networks
Translational Cancer Research, 2018 In recent years, advances in bioinformatics approaches have allowed a systematic characterization of circular RNAs (circRNAs) across a variety of cell types. Demonstration of cell type specificity, regulated expression, and conservation between species all suggest that circRNAs have functional importance.
Apratim, Mitra +2 more
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Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
The Journal of Reproduction and Development, 2020 Circular RNA (circRNA) plays a key role in the development and progression of several diseases; however, its role in intrauterine adhesions (IUAs) is not well understood.
Wei XIE +5 more
doaj +1 more source
Flavonoids Inhibit Cancer by Regulating the Competing Endogenous RNA Network
Frontiers in Oncology, 2022 Flavonoids are present in a wide range of plants. They have been used in the treatment of cancer, but the mechanism underlying this activity is unclear.
Chengshun Li +6 more
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Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Hepatocellular carcinoma (HCC) is a common and lethal type of cancer worldwide. The importance of non-coding RNAs such as long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs) have been recognized in the ...
Mohammad Donyavi +2 more
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The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia
BMC Cancer, 2021 Background As one of the novel molecules, circRNA has been identified closely involved in the pathogenesis of many diseases. However, the function of circRNA in acute myeloid leukemia (AML) still remains unknown.
Siyuan Zhang
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Effect of SARS-CoV-2 infection on host competing endogenous RNA and miRNA network [PDF]
, 2021 Competing endogenous RNAs (ceRNA) play a crucial role in cell functions. Computational methods that provide large-scale analysis of the interactions between miRNAs and their competitive targets can contribute to the understanding of ceRNA regulations and
Alper Yilmaz +3 more
core +1 more source
Differently Expressed Circular RNAs in Lacrimal Sacs From Patients With Chronic Dacryocystitis
Frontiers in Genetics, 2022 This study was designed to identify differently expressed circular RNAs (circRNAs) and investigate their potential roles in lacrimal sacs from patients with chronic dacryocystitis.
Yue Li +11 more
doaj +1 more source
Long Non-Coding RNA- Associated Competing Endogenous RNA Axes in T-Cells in Multiple Sclerosis
Frontiers in Immunology, 2021 Multiple sclerosis (MS) is an immune-mediated demyelinating and degenerative disease with unknown etiology. Inappropriate response of T-cells to myelin antigens has an essential role in the pathophysiology of MS.
Hani Sabaie +11 more
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Cancer Cell International, 2019 Background It is becoming increasingly clear that cancers can rarely be ascribed to just one or a few genomic variations. Genes generally do not function alone, but in groups that function as “networks”. This study aimed to develop a competing endogenous
Min-Er Zhong +5 more
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