Results 31 to 40 of about 1,773,606 (321)
Regulatory Potential of Competing Endogenous RNAs in Myotonic Dystrophies [PDF]
International Journal of Molecular Sciences, 2021 Non-coding RNAs (ncRNAs) have been reported to be implicated in cell fate determination and various human diseases. All ncRNA molecules are emerging as key regulators of diverse cellular processes; however, little is known about the regulatory interaction among these various classes of RNAs.
Edyta Koscianska +2 more
openaire +2 more sources
BMC Gastroenterology, 2022 Background Patients with ulcerative colitis are at an increased risk of developing colorectal cancer with a prolonged disease course. Many studies have shown that alterations in the immune microenvironment play a key role in ulcerative colitis-associated
Shi Yin +8 more
doaj +1 more source
Competing endogenous RNA network for esophageal cancer progression [PDF]
Annals of Translational Medicine, 2021 Esophageal cancer (ESCA) constitutes one of the most common cancers worldwide. The identification of potential biomarkers is important to improving the diagnostic accuracy and treatment efficiency for patients with ESCA. In this study, we aimed to identify biomarkers related to ESCA progression through a comprehensive analysis of long non-coding RNAs ...
Chen, Saihua +9 more
openaire +2 more sources
International Journal on Biological Sciences, 2021 The nuclear paraspeckle assembly transcript 1 (NEAT1) is a long non-coding RNA (lncRNA) that is upregulated in a variety of human cancer types. Increasing evidence has shown that the elevation of NEAT1 in cancer cells promotes cell growth, migration, and
Kun Li +4 more
semanticscholar +1 more source
Integrated analysis of competing endogenous RNA in esophageal carcinoma [PDF]
Journal of Gastrointestinal Oncology, 2021 The Competing endogenous RNA (CeRNA) network plays important roles in the development and progression of multiple human cancers. Increasing attention has been paid to CeRNA in esophageal carcinoma (ESCA).We explored The Cancer Genome Atlas (TCGA) database and then analyzed the RNAs of 142 samples to obtain long non-coding RNAs (lncRNAs), micro RNAs ...
Nanzheng, Chen +5 more
openaire +2 more sources
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
Roles of competing endogenous RNAs in gastric cancer [PDF]
Briefings in Functional Genomics, 2015 Long noncoding RNA (lncRNA) is >200 nucleotides long and lacks coding ability. LncRNA was regarded as transcript noise, until emerging results showed its roles in development, homeostasis and carcinogenesis. LncRNAs containing microRNA (miRNA) response elements could compete with the miRNA target gene and regulate its expression through decreasing free
Ye, Hu +3 more
openaire +2 more sources
BMC Plant Biology, 2021 Background Water deficit is an abiotic stress that retards plant growth and destabilizes crop production. Long non coding RNAs (lncRNAs) are a class of non-coding endogenous RNAs that participate in diverse cellular processes and stress responses in ...
Jiajia Chen, Yuqing Zhong, Xin Qi
semanticscholar +1 more source
PceRBase: a database of plant competing endogenous RNA [PDF]
Nucleic Acids Research, 2016 Competition for microRNA (miRNA) binding between RNA molecules has emerged as a novel mechanism for the regulation of eukaryotic gene expression. Competing endogenous RNA (ceRNA) can act as decoys for miRNA binding, thereby forming a ceRNA network by regulating the abundance of other RNA transcripts which share the same or similar microRNA response ...
Chunhui Yuan +6 more
openaire +2 more sources
Respiratory Research, 2020 Background Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases.
Yifang Liao +5 more
doaj +1 more source