Results 11 to 20 of about 1,773,606 (321)
Modelling Competing Endogenous RNA Networks. [PDF]
PLoS ONE, 2013 MicroRNAs (miRNAs) are small RNA molecules, about 22 nucleotide long, which post-transcriptionally regulate their target messenger RNAs (mRNAs).
Carla Bosia +2 more
doaj +10 more sources
Competing endogenous RNA crosstalk at system level. [PDF]
PLoS Computational Biology, 2019 microRNAs (miRNAs) regulate gene expression at post-transcriptional level by repressing target RNA molecules. Competition to bind miRNAs tends in turn to correlate their targets, establishing effective RNA-RNA interactions that can influence expression ...
Mattia Miotto +2 more
doaj +9 more sources
Competing Endogenous RNA: The Key to Posttranscriptional Regulation [PDF]
The Scientific World Journal, 2014 Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA.
Rituparno Sen +4 more
doaj +6 more sources
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019 Circular RNAs (circRNAs) are a class of covalently closed non-coding RNAs and play crucial regulatory roles in human cancer biology. The purpose of the present study was to explore the expression pattern and biological role of circular RNA PVT1 (circPVT1)
Si Qin +5 more
semanticscholar +2 more sources
Long Noncoding Competing Endogenous RNA Networks in Pancreatic Cancer
Frontiers in Oncology, 2021 Pancreatic cancer (PC) is a highly malignant disease characterized by insidious onset, rapid progress, and poor therapeutic effects. The molecular mechanisms associated with PC initiation and progression are largely insufficient, hampering the ...
Guangbing Xiong +10 more
doaj +3 more sources
Scientific Reports, 2021 Schizophrenia (SCZ) is a serious psychiatric condition with a 1% lifetime risk. SCZ is one of the top ten global causes of disabilities. Despite numerous attempts to understand the function of genetic factors in SCZ development, genetic components in SCZ
Hani Sabaie +7 more
doaj +2 more sources
Competing endogenous RNA (ceRNA) networks in Parkinson's disease: A systematic review
Frontiers in Cellular Neuroscience, 2023 Parkinson's disease (PD) is a distinctive clinical syndrome with several causes and clinical manifestations. Aside from an infectious cause, PD is a rapidly developing neurological disorder with a global rise in frequency.
Mohammad Reza Asadi +13 more
doaj +2 more sources
Emerging Microbes and Infections, 2020 Circular RNAs (circRNAs) are an integral component of the host competitive endogenous RNA (ceRNA) network. These noncoding RNAs are characterized by their unique splicing reactions to form covalently closed loop structures and play important RNA ...
Feifei Yin, Chan Jf, Shuofeng Yuan
exaly +2 more sources
Molecular Cell, 2016 Summary Expression changes of competing endogenous RNAs (ceRNAs) have been proposed to influence microRNA (miRNA) activity and thereby regulate other transcripts containing miRNA-binding sites.
Sean E McGeary +2 more
exaly +2 more sources
Long Non-Coding RNA- Associated Competing Endogenous RNA Axes in T-Cells in Multiple Sclerosis
Frontiers in Immunology, 2021 Multiple sclerosis (MS) is an immune-mediated demyelinating and degenerative disease with unknown etiology. Inappropriate response of T-cells to myelin antigens has an essential role in the pathophysiology of MS.
Hani Sabaie +11 more
doaj +3 more sources