Results 11 to 20 of about 299,250 (314)

Modelling Competing Endogenous RNA Networks. [PDF]

open access: yesPLoS ONE, 2013
MicroRNAs (miRNAs) are small RNA molecules, about 22 nucleotide long, which post-transcriptionally regulate their target messenger RNAs (mRNAs).
Carla Bosia   +2 more
doaj   +11 more sources

Competing endogenous RNA crosstalk at system level. [PDF]

open access: yesPLoS Computational Biology, 2019
microRNAs (miRNAs) regulate gene expression at post-transcriptional level by repressing target RNA molecules. Competition to bind miRNAs tends in turn to correlate their targets, establishing effective RNA-RNA interactions that can influence expression ...
Mattia Miotto   +2 more
doaj   +9 more sources

Competing Endogenous RNA: The Key to Posttranscriptional Regulation [PDF]

open access: yesThe Scientific World Journal, 2014
Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA.
Rituparno Sen   +4 more
doaj   +6 more sources

Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression [PDF]

open access: yesMolecular Cell, 2016
Summary Expression changes of competing endogenous RNAs (ceRNAs) have been proposed to influence microRNA (miRNA) activity and thereby regulate other transcripts containing miRNA-binding sites.
Sean E Mcgeary   +2 more
exaly   +3 more sources

Revealing Landscape of Competing Endogenous RNA Networks in Sepsis-Induced Cardiovascular Diseases [PDF]

open access: yesReviews in Cardiovascular Medicine, 2023
Cardiovascular dysfunction induced by sepsis is one of the most common phenotypes of cardiovascular diseases (CVDs), which is closely related to the high mortality of sepsis and is an urgent health problem to be solved worldwide. Unfortunately, the exact
Wei Xiong   +4 more
doaj   +4 more sources

lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA. [PDF]

open access: yesPLoS ONE, 2014
Long noncoding RNA (lncRNA) influences post-transcriptional regulation by interfering with the microRNA (miRNA) pathways, acting as competing endogenous RNA (ceRNA).
Shaoli Das   +3 more
doaj   +3 more sources

Circular RNA PVT1 acts as a competing endogenous RNA for miR-497 in promoting non-small cell lung cancer progression. [PDF]

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019
Circular RNAs (circRNAs) are a class of covalently closed non-coding RNAs and play crucial regulatory roles in human cancer biology. The purpose of the present study was to explore the expression pattern and biological role of circular RNA PVT1 (circPVT1)
Si Qin   +5 more
semanticscholar   +2 more sources

Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia

open access: yesScientific Reports, 2021
Schizophrenia (SCZ) is a serious psychiatric condition with a 1% lifetime risk. SCZ is one of the top ten global causes of disabilities. Despite numerous attempts to understand the function of genetic factors in SCZ development, genetic components in SCZ
Hani Sabaie   +7 more
doaj   +2 more sources

Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation

open access: yesEmerging Microbes and Infections, 2020
Circular RNAs (circRNAs) are an integral component of the host competitive endogenous RNA (ceRNA) network. These noncoding RNAs are characterized by their unique splicing reactions to form covalently closed loop structures and play important RNA ...
Feifei Yin, Chan Jf, Shuofeng Yuan
exaly   +2 more sources

Expression profiling dataset of competing endogenous RNA in pre-eclampsia

open access: yesData in Brief, 2019
This data descriptor is an extended version of the methodologies which have been described in a related paper [1]; its purpose is to disseminate the raw data and analyzed data produced in this experiment. For more insight please see the research article,
Xiaopeng Hu   +5 more
doaj   +3 more sources

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