Results 11 to 20 of about 312,740 (284)
Competing Endogenous RNA: The Key to Posttranscriptional Regulation [PDF]
The Scientific World Journal, 2014 Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA.
Rituparno Sen +4 more
doaj +6 more sources
Competing endogenous RNA crosstalk at system level.
PLoS Computational Biology, 2019 microRNAs (miRNAs) regulate gene expression at post-transcriptional level by repressing target RNA molecules. Competition to bind miRNAs tends in turn to correlate their targets, establishing effective RNA-RNA interactions that can influence expression ...
Mattia Miotto +2 more
doaj +8 more sources
Competing Endogenous RNA Networks as Biomarkers in Neurodegenerative Diseases [PDF]
International Journal of Molecular Sciences, 2020 Protein aggregation is classically considered the main cause of neuronal death in neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration of RNA metabolism is a key factor in the etiopathogenesis of these complex disorders.
Leticia Moreno-García +10 more
openaire +5 more sources
Long Noncoding Competing Endogenous RNA Networks in Pancreatic Cancer [PDF]
Frontiers in Oncology, 2021 Pancreatic cancer (PC) is a highly malignant disease characterized by insidious onset, rapid progress, and poor therapeutic effects. The molecular mechanisms associated with PC initiation and progression are largely insufficient, hampering the ...
Guangbing Xiong +10 more
doaj +3 more sources
lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA. [PDF]
PLoS ONE, 2014 Long noncoding RNA (lncRNA) influences post-transcriptional regulation by interfering with the microRNA (miRNA) pathways, acting as competing endogenous RNA (ceRNA).
Shaoli Das +3 more
doaj +4 more sources
Flavonoids Inhibit Cancer by Regulating the Competing Endogenous RNA Network
Frontiers in Oncology, 2022 Flavonoids are present in a wide range of plants. They have been used in the treatment of cancer, but the mechanism underlying this activity is unclear.
Chengshun Li +6 more
doaj +3 more sources
Constructing a competing endogenous RNA network for osteoarthritis [PDF]
Annals of Translational Medicine, 2022 Osteoarthritis (OA) is one of the most common diseases in elderly people; however, the correlation between molecular alterations and the occurrence and progression of OA are still not well understood. We conducted this study to investigate the molecular changes in OA via the competing endogenous ribonucleic acid (ceRNA) network.We downloaded the ...
Hua, Shu-Liang +5 more
openaire +2 more sources
Competing endogenous RNA network for esophageal cancer progression [PDF]
Annals of Translational Medicine, 2021 Esophageal cancer (ESCA) constitutes one of the most common cancers worldwide. The identification of potential biomarkers is important to improving the diagnostic accuracy and treatment efficiency for patients with ESCA. In this study, we aimed to identify biomarkers related to ESCA progression through a comprehensive analysis of long non-coding RNAs ...
Chen, Saihua +9 more
openaire +2 more sources
Competing endogenous RNAs in lung cancer
Cancer Biology and Medicine, 2021 Competing endogenous RNAs (ceRNAs) containing microRNA response elements can competitively interact with microRNA via miRNA response elements, which can combine non-coding RNAs with protein-coding RNAs through complex ceRNA networks. CeRNAs include non-coding RNAs (long non-coding RNAs, circular RNAs, and transcribed pseudogenes) and protein-coding ...
Meilian Zhao, Jianguo Feng, Liling Tang
openaire +4 more sources
Competing endogenous RNA database [PDF]
Bioinformation, 2012 A given mRNA can be regulated by interactions with miRNAs and in turn the availability of these miRNAs can be regulated by their interactions with alternate mRNAs. The concept of regulation of a given mRNA by alternate mRNA (competing endogenous mRNA) by virtue of interactions with miRNAs through shared miRNA response elements is poised to become a ...
Sarver, Aaron L, Subramanian, Subbaya
openaire +2 more sources