Results 51 to 60 of about 299,250 (314)
KCNQ1OT1: An Oncogenic Long Noncoding RNA
Biomolecules, 2021 Long noncoding RNAs (lncRNAs) are transcripts greater than 200 nucleotides that do not code for proteins but regulate gene expression. Recent studies indicate that lncRNAs are involved in the modulation of biological functions in human disease.
Patrice Cagle +3 more
doaj +1 more source
Analysis of circRNAs and circRNA-associated competing endogenous RNA networks in β-thalassemia
Scientific Reports, 2022 The involvement of circRNAs in β-thalassemia and their actions on fetal hemoglobin (HbF) is unclear. Here, the circRNAs in β-thalassemia carriers with high HbF levels were comprehensively analyzed and compared with those of healthy individuals ...
Fang Yang +9 more
semanticscholar +1 more source
Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Hepatocellular carcinoma (HCC) is a common and lethal type of cancer worldwide. The importance of non-coding RNAs such as long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs) have been recognized in the ...
Mohammad Donyavi +2 more
doaj +1 more source
Competing endogenous RNA (ceRNA) networks in Parkinson's disease: A systematic review
Frontiers in Cellular Neuroscience, 2023 Parkinson's disease (PD) is a distinctive clinical syndrome with several causes and clinical manifestations. Aside from an infectious cause, PD is a rapidly developing neurological disorder with a global rise in frequency.
M. Asadi +10 more
semanticscholar +1 more source
Circular RNAs and competing endogenous RNA (ceRNA) networks
Translational Cancer Research, 2018 In recent years, advances in bioinformatics approaches have allowed a systematic characterization of circular RNAs (circRNAs) across a variety of cell types. Demonstration of cell type specificity, regulated expression, and conservation between species all suggest that circRNAs have functional importance.
Apratim, Mitra +2 more
openaire +2 more sources
The Journal of Reproduction and Development, 2020 Circular RNA (circRNA) plays a key role in the development and progression of several diseases; however, its role in intrauterine adhesions (IUAs) is not well understood.
Wei XIE +5 more
doaj +1 more source
The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia
BMC Cancer, 2021 Background As one of the novel molecules, circRNA has been identified closely involved in the pathogenesis of many diseases. However, the function of circRNA in acute myeloid leukemia (AML) still remains unknown.
Siyuan Zhang
doaj +1 more source
Differently Expressed Circular RNAs in Lacrimal Sacs From Patients With Chronic Dacryocystitis
Frontiers in Genetics, 2022 This study was designed to identify differently expressed circular RNAs (circRNAs) and investigate their potential roles in lacrimal sacs from patients with chronic dacryocystitis.
Yue Li +11 more
doaj +1 more source
Competing endogenous RNA networks and gastric cancer
World Journal of Gastroenterology, 2015 Recent studies have showed that RNAs regulate each other with microRNA (miRNA) response elements (MREs) and this mechanism is known as "competing endogenous RNA (ceRNA)" hypothesis. Long non-coding RNAs (lncRNAs) are supposed to play important roles in cancer.
Lei-Lei, Guo +5 more
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2021 Background: Osteosarcoma (OS) is the most common primary malignant bone tumour in children and adolescents, with rapid growth, frequent metastasis, and a poor prognosis, but its pathogenesis has not been fully elucidated. Exploring the pathogenesis of OS
Tingrui Wu +11 more
doaj +1 more source