Results 71 to 80 of about 1,773,606 (321)

RNA-specific ribonucleotidyl transferases [PDF]

open access: yes, 2007
RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W.   +3 more
core   +1 more source

Long Noncoding RNA LINC01234 Functions as a Competing Endogenous RNA to Regulate CBFB Expression by Sponging miR-204-5p in Gastric Cancer

open access: yesClinical Cancer Research, 2018
Purpose: Long noncoding RNAs (lncRNAs) have emerged as important regulators in a variety of human diseases, including cancers. However, the overall biological roles and clinical significance of most lncRNAs in gastric carcinogenesis are not fully ...
Xin Chen   +12 more
semanticscholar   +1 more source

An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei [PDF]

open access: yes, 2007
RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs.
Schnaufer, Achim; id_orcid   +4 more
core   +1 more source

Molecular Insight Into the Therapeutic Potential of Long Non-coding RNA-Associated Competing Endogenous RNA Axes in Alzheimer’s Disease: A Systematic Scoping Review

open access: yesFrontiers in Aging Neuroscience, 2021
Alzheimer’s disease (AD) is a heterogeneous degenerative brain disorder with a rising prevalence worldwide. The two hallmarks that characterize the AD pathophysiology are amyloid plaques, generated via aggregated amyloid β, and neurofibrillary tangle ...
Hani Sabaie   +7 more
semanticscholar   +1 more source

Long noncoding RNA SNHG6 mainly functions as a competing endogenous RNA in human tumors

open access: yesCancer Cell International, 2020
Increased expression of the small nucleolar RNA host gene 6 (SNHG6) has been reported in different cancers, such as hepatocellular carcinoma, colorectal cancer, and lung cancer.
Hui-shan Wang   +4 more
doaj   +1 more source

Long Noncoding RNA IFITM4P Regulates Host Antiviral Responses by Acting as a Competing Endogenous RNA

open access: yesJournal of Virology, 2021
lncRNAs play important roles in various biological processes, but their involvement in host antiviral responses remains largely unknown. In this study, we revealed that the pseudogene IFITM4P belonging to the IFITM family can transcribe a functional long
Meng Xiao   +9 more
semanticscholar   +1 more source

Progress in Competing Endogenous RNA and Cancer

open access: yesJournal of Cancer Therapy, 2015
The competing endogenous RNA (ceRNA) hypothesis was introduced as a previously unrecognized gene regulatory layer. This is a recently discovered hypothesis about how mRNAs, pseudogene transcripts, long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) regulate post-transcriptional expression by sharing common microRNA response elements (MREs ...
Ting Zhang, Weiguo Huang
openaire   +2 more sources

Construction of circRNA-miRNA-mRNA Network for Exploring Underlying Mechanisms of Lubrication Disorder

open access: yesFrontiers in Cell and Developmental Biology, 2021
Lubrication disorder is a common health issue that manifests as insufficient sexual arousal at the beginning of sex. It often causes physical and psychological distress.
Shengnan Cong   +7 more
doaj   +1 more source

Construction of lncRNA-related competing endogenous RNA network and identification of hub genes in recurrent implantation failure

open access: yesReproductive Biology and Endocrinology, 2021
Background The mechanism of recurrent implantation failure (RIF) is unclear at present and poor endometrial receptivity may be one of the leading reasons.
Jialyu Huang   +7 more
semanticscholar   +1 more source

Long noncoding RNA associated-competing endogenous RNAs in gastric cancer [PDF]

open access: yesScientific Reports, 2014
Some long noncoding RNAs (lncRNAs) play important roles in the regulation of gene expression by acting as competing endogenous RNAs (ceRNAs). However, the roles of lncRNA associated-ceRNAs in oncogenesis are not fully understood. Here, based on lncRNA microarray data of gastric cancer, bioinformatic algorithm miRcode and microRNA (miRNA) targets ...
Xia, Tian   +6 more
openaire   +2 more sources

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