Results 61 to 70 of about 299,250 (314)

Molecular mechanisms of thyroid cancer: A competing endogenous RNA (ceRNA) point of view.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
Thyroid cancer (TC) is the most prevalent malignancy of the endocrine system. Although there are few treatment choices for individuals with TC, determining the underlying mechanisms is essential for treatment due to the complex carcinogenesis of this ...
Yang Liu   +4 more
semanticscholar   +1 more source

Flavonoids Inhibit Cancer by Regulating the Competing Endogenous RNA Network

open access: yesFrontiers in Oncology, 2022
Flavonoids are present in a wide range of plants. They have been used in the treatment of cancer, but the mechanism underlying this activity is unclear.
Chengshun Li   +6 more
doaj   +1 more source

Analyzing the Interactions of mRNAs and ncRNAs to Predict Competing Endogenous RNA Networks in Osteosarcoma Chemo-Resistance.

open access: yesMolecular Therapy, 2019
Chemo-resistance is a huge obstacle encountered in the osteosarcoma (OS) treatment. Protein-coding mRNAs, as well as non-coding RNAs (ncRNAs), including long ncRNA (lncRNA), circular RNA (circRNA), and microRNA (miRNA), have been demonstrated to play an ...
K. Zhu   +5 more
semanticscholar   +1 more source

Effect of SARS-CoV-2 infection on host competing endogenous RNA and miRNA network [PDF]

open access: yes, 2021
Competing endogenous RNAs (ceRNA) play a crucial role in cell functions. Computational methods that provide large-scale analysis of the interactions between miRNAs and their competitive targets can contribute to the understanding of ceRNA regulations and
Alper Yilmaz   +3 more
core   +1 more source

Long Non-Coding RNA- Associated Competing Endogenous RNA Axes in T-Cells in Multiple Sclerosis

open access: yesFrontiers in Immunology, 2021
Multiple sclerosis (MS) is an immune-mediated demyelinating and degenerative disease with unknown etiology. Inappropriate response of T-cells to myelin antigens has an essential role in the pathophysiology of MS.
Hani Sabaie   +11 more
doaj   +1 more source

LncRNA H19 regulates PI3K–Akt signal pathway by functioning as a ceRNA and predicts poor prognosis in colorectal cancer: integrative analysis of dysregulated ncRNA-associated ceRNA network

open access: yesCancer Cell International, 2019
Background It is becoming increasingly clear that cancers can rarely be ascribed to just one or a few genomic variations. Genes generally do not function alone, but in groups that function as “networks”. This study aimed to develop a competing endogenous
Min-Er Zhong   +5 more
doaj   +1 more source

Long Noncoding RNA (lncRNA)-Mediated Competing Endogenous RNA Networks Provide Novel Potential Biomarkers and Therapeutic Targets for Colorectal Cancer

open access: yesInternational Journal of Molecular Sciences, 2019
Colorectal cancer (CRC) is the third most common cancer and has a high metastasis and reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role in CRC growth and metastasis.
Liye Wang   +5 more
semanticscholar   +1 more source

A Key mRNA-miRNA-lncRNA Competing Endogenous RNA Triple Sub-network Linked to Diagnosis and Prognosis of Hepatocellular Carcinoma

open access: yesFrontiers in Oncology, 2020
Growing evidence has illustrated critical roles of competing endogenous RNA (ceRNA) regulatory network in human cancers including hepatocellular carcinoma.
Junjie Zhang, Weiyang Lou
semanticscholar   +1 more source

Competing Endogenous RNA Regulations in Neurodegenerative Disorders: Current Challenges and Emerging Insights [PDF]

open access: yes, 2018
The past decade has witnessed exciting breakthroughs that have contributed to the richness and complexity of a burgeoning modern RNA world, and one particular breakthrough—the competing endogenous RNA (ceRNA) hypothesis—has been described as the “Rosetta
Jun Wan, Yifei Cai
core   +3 more sources

Long Noncoding RNA LINC01234 Functions as a Competing Endogenous RNA to Regulate CBFB Expression by Sponging miR-204-5p in Gastric Cancer

open access: yesClinical Cancer Research, 2018
Purpose: Long noncoding RNAs (lncRNAs) have emerged as important regulators in a variety of human diseases, including cancers. However, the overall biological roles and clinical significance of most lncRNAs in gastric carcinogenesis are not fully ...
Xin Chen   +12 more
semanticscholar   +1 more source

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