Icariin inhibits proliferation and migration of VSMCs via LncRNA H19 competitively binding to HuR [PDF]
Scientific ReportsDeveloping new anti-atherosclerotic agents and exploring their mechanistic actions is required. This study defined the molecular mechanism of icariin (ICA) in human aortic smooth muscle cells (HA-VSMCs) proliferation and migration by focusing on lncRNA ...
Yibing Zhang +3 more
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lncRNA H19 facilitates vascular neointima formation by targeting miR-125a-3p/FLT1 axis [PDF]
Acta Biochimica et Biophysica SinicaThe aberrant proliferation and migration of vascular smooth muscle cells (VSMCs) contribute to the development of neointima formation in vascular restenosis. This study aims to explore the function of the long noncoding RNA H19 in neointima formation.
Jiang Rengui +15 more
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Targeting the dual miRNA/BMP2 network: LncRNA H19-mediated temozolomide resistance unveils novel therapeutic strategies in glioblastoma [PDF]
Frontiers in OncologyBackgroundLong noncoding RNA (lncRNA) is known to not only be involved in various biological processes but also to play a crucial role in chemotherapy resistance.
Qiudan Chen +5 more
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Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis
Bioactive Materials, 2022 Curcumenol, an effective ingredient of Wenyujin, has been reported that exerted its antitumor potential in a few cancer types. However, the effect and molecular mechanism of curcumenol in lung cancer are largely unknown.
Jiao Feng, Tian Xie, Qibiao Wu
exaly +3 more sources
Association between lncRNA H19 and osteoporosis in postmenopausal patients with type 2 diabetes mellitus [PDF]
Journal of Orthopaedic Surgery and ResearchBackground This study aimed to assess the expression level of long non-coding RNA H19 (lncRNA H19) in peripheral blood mononuclear cells (PBMCs) of postmenopausal patients with type 2 diabetes mellitus (T2DM) with comorbid osteoporosis (T2DM-OP), and to ...
Teng Yang +5 more
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Mechanosensitive lncRNA H19 promotes chondrocyte autophagy, but not pyroptosis, by targeting miR-148a in post-traumatic osteoarthritis [PDF]
Non-coding RNA ResearchObjective: Investigating whether mechanosensitive lncRNA H19 can directly target miR-148a to alleviate cartilage damage in post-traumatic osteoarthritis (PTOA).
Xuchang Zhou +9 more
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Role of LncRNA H19 in tumor progression and treatment
Molecular and Cellular ProbesAs one of the earliest discovered lncRNA molecules, lncRNA H19 is usually expressed in large quantities during embryonic development and is involved in cell differentiation and tissue formation.
Linjing Li +5 more
exaly +3 more sources
Down-regulation of lncRNA-H19 expression promotes apoptosis and autophagy of human keloid fibroblasts [PDF]
Jichu yixue yu linchuang, 2022 Objective To investigate the effects of down-regulation of long non-coding RNA-H19 (lncRNA-H19) expression on apoptosis and autophagy of human keloid fibroblast cell line and to explore potential mechanism.
HUANG Yun, XU Xi-sheng, CHEN Kai, HE Xiu
doaj +1 more source
Neural Regeneration Research, 2023 LncRNA (long non-coding RNA) H19 is a transcript of the H19 gene that is expressed during embryogenesis. We previously discovered a role for circular lncRNA H19 in the onset and prognosis of cerebral ischemic stroke.
Jue Wang +4 more
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Role of LncRNA H19 in promoting endometrial deciduation
陆军军医大学学报, 2023 Objective To explore the effect of LncRNA H19 on endometrial decidualization. Methods The expression of LncRNA H19 in decidual tissues of spontaneous abortion and induced abortion was detected by RT-qPCR; The expression of LncRNA H19 in non-pregnant ...
WANG Tingting +4 more
doaj +1 more source