Results 1 to 10 of about 28,609 (105)

Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis

Bioactive Materials, 2022
Curcumenol, an effective ingredient of Wenyujin, has been reported that exerted its antitumor potential in a few cancer types. However, the effect and molecular mechanism of curcumenol in lung cancer are largely unknown.
Jiao Feng, Tian Xie, Qibiao Wu
exaly   +4 more sources

The Potential Utility of Circulating Oncofetal H19 Derived miR-675 Expression versus Tissue lncRNA-H19 Expression in Diagnosis and Prognosis of HCC in Egyptian Patients

Biomolecules, 2022
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Interestingly, lncRNA-H19 acts independently in HCC and influences miR-675 expressions.
Shimaa Abdelsattar, Dina Sweed, Hala F. M. Kamel, Zeinab A. Kasemy, Abdallah M. Gameel, Hassan Elzohry, Omnia Ameen, Eman Ibrahim Elgizawy, Ahmed Sallam, Asmaa Mosbeh, Mahmoud S. Abdallah, Fatma O. Khalil, Hiba S. Al-Amodi, Sally M. El-Hefnway   +13 more
doaj   +2 more sources

Relationship between the Levels of lncRNA H19 in Plasma and Different Adipose Tissue Depots with Patients’ Response to Bariatric Surgery

Life, 2022
Bariatric surgery represents a widespread approach to treating morbid obesity. The search for biomarkers to identify patients to whom this type of treatment will be most effective is needed.
Marina S. Artemyeva, Ludmila B. Vasileva, Yi Ma, Kirill A. Kondratov, Anton V. Fedorov, Anna A. Kostareva, Sofia E. Lapshina, Anna D. Anopova, Nikolai P. Likhonosov, Alexander E. Neymark, Alina Yu. Babenko, Evgeny V. Shlyakhto   +11 more
doaj   +2 more sources

Assessment of Circulating lncRNA H19 in Ankylosing Spondylitis Patients and Its Correlation with Disease Activity

Journal of Personalized Medicine, 2023
Ankylosing spondylitis (AS) is a chronic inflammatory disease that results in severe pain and stiffness in the joints. The causes and pathophysiology of AS are still largely unknown.
Murad Mubaraki, Marwa A Shabana, Marwa Mohammed Esawy   +2 more
exaly   +2 more sources

Hypomethylation of the LncRNA H19 promoter accelerates osteogenic differentiation of vascular smooth muscle cells by activating the Erk1/2 pathways

Journal of International Medical Research
Objective Vascular calcification is a common chronic kidney disease complication. This study aimed to investigate the function of long non-coding RNA (LncRNA) H19 in vascular calcification to explore new therapeutic strategies.
Taoxia Wang, Meijuan Cheng, Jingjing Jin, Yaling Bai, Dongxue Zhang, Shenglei Zhang, Jinsheng Xu   +6 more
doaj   +2 more sources

Long non-coding RNA H19 promotes cervical cancer development via targeting the microRNA-140/ALDH1A1 axis

European Journal of Medical Research
Background Dysregulation of long non-coding RNA H19 (lncRNA H19) is involved in cervical cancer (CC) progression. This study aims to unveil the specific role and relevant mechanism of lncRNA H19 in CC. Methods The expression of lncRNA H19 in CC cells was
Jie Ming, Fang Cheng, Yating Fu, Meng Zhang, Qian Rou, Kaixiong Liu, Zinati Nuertai, Shanshan Xu, Ling Tao, Alfira Abudujapar, Ying Liu   +10 more
doaj   +2 more sources

The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis

International Journal of Molecular Sciences, 2017
Long non-coding RNA (lncRNA), a novel and effective modulator in carcinogenesis, has become a study hotspot in recent years. The imprinted oncofetal lncRNA H19 is one of the first identified imprinted lncRNAs with a high expression level in embryogenesis
Jun Yu, Wei Kang, Alfred S. Cheng
exaly   +2 more sources

Long noncoding RNA H19 is a critical oncogenic driver and contributes to epithelial-mesenchymal transition in papillary thyroid carcinoma

Cancer Management and Research, 2019
Wei-Quan Liang,1,* De Zeng,2,* Chun-Fa Chen,1 Shu-Ming Sun,1 Xiao-Feng Lu,1 Chun-yan Peng,3 Hao-Yu Lin1 1Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515000, People ...
Liang WQ, Zeng D, Chen CF, Sun SM, Lu XF, Peng CY, Lin HY   +6 more
doaj   +1 more source

Mechanosensitive lncRNA H19 promotes chondrocyte autophagy, but not pyroptosis, by targeting miR-148a in post-traumatic osteoarthritis

Non-coding RNA Research
Objective: Investigating whether mechanosensitive lncRNA H19 can directly target miR-148a to alleviate cartilage damage in post-traumatic osteoarthritis (PTOA).
Xuchang Zhou, Hong Cao, Tao Liao, Weizhong Hua, Ruobing Zhao, Dongxue Wang, Huili Deng, Yajing Yang, ShengYao Liu, Guoxin Ni   +9 more
doaj   +2 more sources

The lncRNA H19/miR-766-3p/S1PR3 Axis Contributes to the Hyperproliferation of Keratinocytes and Skin Inflammation in Psoriasis via the AKT/mTOR Pathway

Mediators of Inflammation, 2021
Background. The pathogenesis of long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) are well studied in psoriasis. However, little is known about how specific lncRNAs and miRNAs affect the mechanism of psoriasis development and which pathways are ...
Yuexi He, Xiran Yin, Jianjun Yan, Xue Li, Qing Sun   +4 more
doaj   +2 more sources