Results 21 to 30 of about 39,808 (145)

Exosome-transported lncRNA H19 regulates insulin-like growth factor-1 via the H19/let-7a/insulin-like growth factor-1 receptor axis in ischemic stroke

Neural Regeneration Research, 2023
LncRNA (long non-coding RNA) H19 is a transcript of the H19 gene that is expressed during embryogenesis. We previously discovered a role for circular lncRNA H19 in the onset and prognosis of cerebral ischemic stroke.
Jue Wang, Bin Cao, Yan Gao, Yu-Hua Chen, Juan Feng   +4 more
doaj   +1 more source

Role of LncRNA H19 in promoting endometrial deciduation

陆军军医大学学报, 2023
Objective To explore the effect of LncRNA H19 on endometrial decidualization. Methods The expression of LncRNA H19 in decidual tissues of spontaneous abortion and induced abortion was detected by RT-qPCR; The expression of LncRNA H19 in non-pregnant ...
WANG Tingting, HUANG Jinglin, MAO Yanhua, ZHANG Yingfeng, SUN Congcong   +4 more
doaj   +1 more source

The Pathogenic Role of Long Non-coding RNA H19 in Atherosclerosis via the miR-146a-5p/ANGPTL4 Pathway

Frontiers in Cardiovascular Medicine, 2021
The abnormally expressed long non-coding RNA (lncRNA) H19 has a crucial function in the development and progression of cardiovascular disease; however, its role in atherosclerosis is yet to be known.
Shi-Feng Huang, Guifang Zhao, Xiao-Fei Peng, Wen-Chu Ye   +3 more
doaj   +1 more source

A prominent role of LncRNA H19 in H. pylori CagA induced DNA damage response and cell malignancy [PDF]

Sci Rep
Helicobacter pylori (H. pylori), together with its CagA, has been implicated in causing DNA damage, cell cycle arrest, apoptosis, and the development of gastric cancer.
Yanhong Li, Yan Zhao, Tingting Huang, Yuan Xie, Xiaofeng He, Liya Bao, Hui Song, Jianjiang Zhou, Qinrong Wang, Zhengrong Wang   +9 more
core   +2 more sources

Knockdown of lncRNA H19 suppresses endometriosis in vivo [PDF]

Brazilian Journal of Medical and Biological Research, 2021
The long noncoding RNA (lncRNA) H19 is involved in the pathogenesis of endometriosis by modulating the proliferation and invasion of ectopic endometrial cells in vitro, but related in vivo studies are rare.
Songping Liu, Weijuan Xin, Qi Lu, Xiaoyan Tang, Fengqin Wang, Wei Shao, Yajiao Zhang, Junjun Qiu, Keqin Hua   +8 more
doaj   +1 more source

LncRNA-H19 in Fibroblasts Promotes Diabetic Wound Healing

, 2022
Cutaneous wound healing in diabetes is impaired and would develop into nonhealing ulcerations. However, the molecular mechanism underlying the wound-healing process remains largely obscure.
Junjie Li (12724), Ning Xu (52890), Pijun Yu (12419326), Jian Guo (191157), Yongkang Jiang (5508881), Xiao Shi (2587357), Qin Hu (152100), Wei Chen (23863)   +7 more
core   +1 more source

Role of long non-coding RNA H19 in the development of osteoporosis

Molecular Medicine, 2021
Background Osteoporosis is a widespread and serious metabolic bone disease. At present, revealing the molecular mechanisms of osteoporosis and developing effective prevention and treatment methods are of great significance to health worldwide.
Senxiang Chen, Da Liu, Zimo Zhou, Sen Qin   +3 more
doaj   +1 more source

Circulating exosomal long non-coding RNA H19 as a potential novel diagnostic and prognostic biomarker for gastric cancer

Journal of International Medical Research, 2020
Objective Long non-coding RNAs (lncRNAs) are involved in carcinogenesis and could be used as diagnostic biomarkers. Our study aimed to elucidate the clinical role of serum exosomal lncRNA H19 in gastric cancer (GC).
Hui Zhou, Weifeng Shen, Hongxing Zou, Qingshan Lv, Pingyang Shao   +4 more
doaj   +1 more source

LncRNA‐H19 gene plays a significant role in regulating glioma cell function

Molecular Genetics & Genomic Medicine, 2021
Background Glioma is an aggressive adult primary cancer, and is characterized by low cure rate, poor prognosis, and high recurrence. The present study aimed to investigate the effect of lncRNA‐H19 gene silencing on glioma cell function.
Ping Liu, Xinqiong Huang, Haijun Wu, Guoling Yin, Liangfang Shen   +4 more
doaj   +1 more source

Pleiotropic cardiac functions controlled by ischemia-induced lncRNA H19

, 2022
S.43-59Myocardial ischemia induces a multifaceted remodeling process in the heart. Novel therapeutic entry points to counteract maladaptive signalling include the modulation of non-coding RNA molecules such as long non-coding RNA (lncRNA).
Frantz, S., Schmidt, A., Ramos, G.C., Just, A., Wollert, K.C., Zimmer, K., Remke, J., Viereck, J., Reamon-Buettner, S.M., Loyer, X., Pich, A., Boulanger, C., Foinquinos, A., Nowak, J., Xiao, K., Kenneweg, F., Wang, Y., Jung, M., Mazlan, S., Fiedler, J., Thum, T., Hobuß, L.   +21 more
core   +1 more source