Results 11 to 20 of about 39,808 (145)

Icariin inhibits proliferation and migration of VSMCs via LncRNA H19 competitively binding to HuR [PDF]

Scientific Reports
Developing new anti-atherosclerotic agents and exploring their mechanistic actions is required. This study defined the molecular mechanism of icariin (ICA) in human aortic smooth muscle cells (HA-VSMCs) proliferation and migration by focusing on lncRNA ...
Yibing Zhang, Peng Huang, Min Li, Zhimin Fan   +3 more
doaj   +2 more sources

lncRNA H19 facilitates vascular neointima formation by targeting miR-125a-3p/FLT1 axis [PDF]

Acta Biochimica et Biophysica Sinica
The aberrant proliferation and migration of vascular smooth muscle cells (VSMCs) contribute to the development of neointima formation in vascular restenosis. This study aims to explore the function of the long noncoding RNA H19 in neointima formation.
Jiang Rengui, He Xuyu, Chen Weidong, Cai Huoying, Su Zhaohai, Xie Zheng, Zhang Bilong, Yang Jiangyong, Wang Yueting, Huang Ling, Cao Gang, Zhong Xiutong, Xie Hui, Zhu Hengqing, Cao Jun, Lu Weiling   +15 more
doaj   +2 more sources

Targeting the dual miRNA/BMP2 network: LncRNA H19-mediated temozolomide resistance unveils novel therapeutic strategies in glioblastoma [PDF]

Frontiers in Oncology
BackgroundLong noncoding RNA (lncRNA) is known to not only be involved in various biological processes but also to play a crucial role in chemotherapy resistance.
Qiudan Chen, Shihao Zhuang, Shuying Chen, Biying Wu, Qingyu Zhou, Weifeng Wang   +5 more
doaj   +2 more sources

Resistance to Doxorubicin Therapy in Breast Cancer Cells Could Be Attenuated by Ligustilide: Impact on Autophagy and LncRNA H19 [PDF]

BMC Complement Med Ther
Background Resistance to DOX in breast cancer (BC) treatment is attributed to multiple mechanisms. The potential of autophagy inhibition in mitigating DOX resistance in BC has yet to be clarified.
Amr, Eman A., Elashmawy, Nahla, El-Feky, Ola A., Khedr, Eman G.   +3 more
core   +2 more sources

rs217727 of lncRNA H19 is Associated with Cervical Cancer Risk in the Chinese Han Population [PDF]

Pharmgenomics Pers Med, 2023
Jie Dai,1,* Shao Zhang,2,* Yuhan Shi,3 Jinmei Xu,2 Weipeng Liu,1 Jia Yang,1 Li Shi,1 Zhiling Yan,2,4 Chuanyin Li1 1Department of Immunogenetics, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College ...
Yang J, Shi L, Yan Z, Li C, Zhang S, Dai J, Xu J, Shi Y, Liu W   +8 more
core   +2 more sources

Association between lncRNA H19 and osteoporosis in postmenopausal patients with type 2 diabetes mellitus [PDF]

Journal of Orthopaedic Surgery and Research
Background This study aimed to assess the expression level of long non-coding RNA H19 (lncRNA H19) in peripheral blood mononuclear cells (PBMCs) of postmenopausal patients with type 2 diabetes mellitus (T2DM) with comorbid osteoporosis (T2DM-OP), and to ...
Teng Yang, Xiuli Feng, Na Wang, Tongyu Zhang, Zhichen Zheng, Guofeng Wang   +5 more
doaj   +2 more sources

Role of LncRNA H19 in tumor progression and treatment

Molecular and Cellular Probes
As one of the earliest discovered lncRNA molecules, lncRNA H19 is usually expressed in large quantities during embryonic development and is involved in cell differentiation and tissue formation.
Linjing Li, Yuting Gao, Boyi Yu, Jiahao Zhang, Guorong Ma, Xiaodong Jin   +5 more
exaly   +3 more sources

Extracellular vesicle-mimetic nanovesicles transport LncRNA-H19 as competing endogenous RNA for the treatment of diabetic wounds

Drug Delivery, 2018
Diabetic wounds, one of the most enervating complications of diabetes mellitus, affect millions of people worldwide annually. Vascular insufficiency, caused by hyperglycemia, is one of the primary causes and categories of diabetic impaired wound healing.
Shi-Cong Tao, Bi-Yu Rui, Qi-Yang Wang, Ding Zhou, Yang Zhang, Shang-Chun Guo   +5 more
doaj   +2 more sources

Down-regulation of lncRNA-H19 expression promotes apoptosis and autophagy of human keloid fibroblasts [PDF]

Jichu yixue yu linchuang, 2022
Objective To investigate the effects of down-regulation of long non-coding RNA-H19 (lncRNA-H19) expression on apoptosis and autophagy of human keloid fibroblast cell line and to explore potential mechanism.
HUANG Yun, XU Xi-sheng, CHEN Kai, HE Xiu
doaj   +1 more source

LncRNA H19 Promotes Gastric Cancer Metastasis via miR-148-3p/SOX-12 Axis [PDF]

Anal Cell Pathol (Amst)
Background. Gastric cancer (GC) is the most common malignant tumor and ranks third in the world. LncRNA H19 (H19), one of the members of lncRNA, is overexpressed in various tumors.
Yazhe Zhou, Haiying Wang, Xin Zhang, Jie Liu, Ge Wang, Rui Jiao, Ying Chen, Qiang Wang, Yanqing Liu, Xiaoru Li, Xue Wu   +10 more
core   +2 more sources