Results 31 to 40 of about 39,808 (145)

β-Elemene Reverses Gefitinib Resistance in NSCLC Cells by Inhibiting lncRNA H19-Mediated Autophagy [PDF]

Pharmaceuticals (Basel)
Lung cancer is a leading cause of mortality worldwide, especially among Asian patients with non-small cell lung cancer (NSCLC) who have epidermal growth factor receptor (EGFR) mutations.
Ruonan Zhang, Xidong Gu, Yintao Zheng, Xinbing Sui, Bo Xiang, Tian Xie, Qianru Zhu, Xiaoqing Gu   +7 more
core   +2 more sources

M1 macrophage‐derived exosomes promote autoimmune liver injury by transferring long noncoding RNA H19 to hepatocytes

MedComm, 2023
Exosomes mediate intercellular communication by transmitting active molecules. The function of long noncoding RNA (lncRNA) H19 in autoimmune liver injury is unclear.
Yongting Zhang, Liang Hong, Xuehui Li, Yuyu Li, Xujun Zhang, Jingjing Jiang, Fan Shi, Hongyan Diao   +7 more
doaj   +1 more source

H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase [PDF]

, 2015
DNA methylation is essential for mammalian development and physiology. Here we report that the developmentally regulated H19 lncRNA binds to and inhibits S-adenosylhomocysteine hydrolase (SAHH), the only mammalian enzyme capable of hydrolysing S ...
Men, Yi, Carmichael, Gordon G, Huang, Yingqun, Yang, Lihua, Xie, Juanke, Lu, Lingeng, Zhang, Na, Zhong, Tianyu, Taylor, Hugh S, Chung, Hunter, Zhou, Jichun, Müller, Martin, Giang, Karolyn, Sun, Xueguang   +13 more
core   +2 more sources

RNA-binding Protein LIN28a Regulates New Myocyte Formation in the Heart via lncRNA-H19

, 2023
 Background: Developmental cardiac tissue holds remarkable capacity to regenerate after injury and consists of regenerative mononuclear and diploid cardiomyocytes (MNDCMs).
Jennifer Pennise (14432220), Tej M. Patel (10106364), Tao Wang (12008), Michael Behanan (14432214), Robert C. Hoy (8807582), Vagner Oliveira-Carvalho Rigaud (12706817), Mohsin Khan (352381), Justin Kurian (4459243), Lindsay Kraus (9013847), Isabella Brosious (14432217), Sadia Mohsin (541545), Steven R. Houser (6439097), Clare Zarka (14432211), Jaslyn Johnson (14432223)   +13 more
core   +1 more source

Predictive value of plasma long non-coding RNA H19 in neoadjuvant therapy for breast cancer [PDF]

Zhongguo aizheng zazhi, 2022
Background and purpose: Long noncoding RNA (LncRNA) plays an important role in the development of distant metastasis and drug resistance of tumors, and it is highly expressed in breast cancer tissues and plasma of breast cancer patients.
CHEN Anli, SHEN Haoyuan, YANG Shixiong, DENG Chunyan, HU Chaohua, LIU Hanzhong, WANG Shu, QIAN Fang
doaj   +3 more sources

Silencing of the lncRNA H19 enhances sensitivity to X-ray and carbon-ions through the miR-130a-3p /WNK3 signaling axis in NSCLC cells

Cancer Cell International, 2021
Background The lncRNA H19 is believed to act as an oncogene in various types of tumors and is considered to be a therapeutic target and diagnostic marker.
Xueshan Zhao, Xiaodong Jin, Qiuning Zhang, Ruifeng Liu, Hongtao Luo, Zhen Yang, Yichao Geng, Shuangwu Feng, Chengcheng Li, Lina Wang, Xiaohu Wang, Qiang Li   +11 more
doaj   +1 more source

LncRNA H19 as a Competing Endogenous RNA to Regulate AQP Expression in the Intestinal Barrier of IBS-D Patients

Frontiers in Physiology, 2021
ObjectiveThe study aimed to investigate the role of Long non-coding RNA (LncRNA) H19 in the pathogenesis of Diarrhea Irritable Bowel Syndrome (IBS-D), and further to the regulatory effect of LncRNA H19 on AQP1, 3 in the intestinal mucosa of IBS-D ...
Guanqun Chao, Zhaojun Wang, Yi Yang, Shuo Zhang   +3 more
doaj   +1 more source

Long noncoding RNA H19 upregulates vascular endothelial growth factor A to enhance mesenchymal stem cells survival and angiogenic capacity by inhibiting miR-199a-5p

Stem Cell Research & Therapy, 2018
Background Currently, the overall therapeutic efficiency of mesenchymal stem cells (MSCs) transplantation for the treatment of cardiovascular disease is not satisfactory.
Jingying Hou, Lingyun Wang, Quanhua Wu, Guanghui Zheng, Huibao Long, Hao Wu, Changqing Zhou, Tianzhu Guo, Tingting Zhong, Lei Wang, Xuxiang Chen, Tong Wang   +11 more
doaj   +1 more source

H19 and TUG1 lncRNAs as Novel Biomarkers for Irritable Bowel Syndrome in Diabetic Patients

Biomedicines, 2022
Introduction: Irritable bowel syndrome (IBS) is a gastrointestinal disorder due to enteric nervous system impairment that produces different patterns of digestion. IBS is a common finding in diabetic patients.
Marwa M. Esawy, Noorah Saleh Al-Sowayan, Maysa A. Mobasher, Amir Abd-elhameed, Elsayed S. Abd elbaser, Shereen A. Baioumy, Marwa A. Shabana   +6 more
doaj   +1 more source

Association of serum lncRNA H19 expression with inflammatory and oxidative stress markers and routine biochemical parameters in chronic kidney disease

, 2021
Background: Chronic kidney disease (CKD) is a disorder that affects millions worldwide, and current treatment options aiming at inhibiting the progression of kidney damage are limited.
Okuyan, Hamza Malik, TERZİ, MENDERES YUSUF, Begen, Mehmet A., TURGUT, FARUK HİLMİ, DOĞAN, SERDAR   +4 more
core   +1 more source