Results 21 to 30 of about 39,827 (164)

Knockdown of lncRNA H19 suppresses endometriosis in vivo [PDF]

Brazilian Journal of Medical and Biological Research, 2021
The long noncoding RNA (lncRNA) H19 is involved in the pathogenesis of endometriosis by modulating the proliferation and invasion of ectopic endometrial cells in vitro, but related in vivo studies are rare.
Songping Liu, Weijuan Xin, Qi Lu, Xiaoyan Tang, Fengqin Wang, Wei Shao, Yajiao Zhang, Junjun Qiu, Keqin Hua   +8 more
doaj   +1 more source

LncRNA-H19 in Fibroblasts Promotes Diabetic Wound Healing

, 2022
Cutaneous wound healing in diabetes is impaired and would develop into nonhealing ulcerations. However, the molecular mechanism underlying the wound-healing process remains largely obscure.
Junjie Li (12724), Ning Xu (52890), Pijun Yu (12419326), Jian Guo (191157), Yongkang Jiang (5508881), Xiao Shi (2587357), Qin Hu (152100), Wei Chen (23863)   +7 more
core   +1 more source

Role of long non-coding RNA H19 in the development of osteoporosis

Molecular Medicine, 2021
Background Osteoporosis is a widespread and serious metabolic bone disease. At present, revealing the molecular mechanisms of osteoporosis and developing effective prevention and treatment methods are of great significance to health worldwide.
Senxiang Chen, Da Liu, Zimo Zhou, Sen Qin   +3 more
doaj   +1 more source

Circulating exosomal long non-coding RNA H19 as a potential novel diagnostic and prognostic biomarker for gastric cancer

Journal of International Medical Research, 2020
Objective Long non-coding RNAs (lncRNAs) are involved in carcinogenesis and could be used as diagnostic biomarkers. Our study aimed to elucidate the clinical role of serum exosomal lncRNA H19 in gastric cancer (GC).
Hui Zhou, Weifeng Shen, Hongxing Zou, Qingshan Lv, Pingyang Shao   +4 more
doaj   +1 more source

LncRNA‐H19 gene plays a significant role in regulating glioma cell function

Molecular Genetics & Genomic Medicine, 2021
Background Glioma is an aggressive adult primary cancer, and is characterized by low cure rate, poor prognosis, and high recurrence. The present study aimed to investigate the effect of lncRNA‐H19 gene silencing on glioma cell function.
Ping Liu, Xinqiong Huang, Haijun Wu, Guoling Yin, Liangfang Shen   +4 more
doaj   +1 more source

Pleiotropic cardiac functions controlled by ischemia-induced lncRNA H19

, 2022
S.43-59Myocardial ischemia induces a multifaceted remodeling process in the heart. Novel therapeutic entry points to counteract maladaptive signalling include the modulation of non-coding RNA molecules such as long non-coding RNA (lncRNA).
Frantz, S., Schmidt, A., Ramos, G.C., Just, A., Wollert, K.C., Zimmer, K., Remke, J., Viereck, J., Reamon-Buettner, S.M., Loyer, X., Pich, A., Boulanger, C., Foinquinos, A., Nowak, J., Xiao, K., Kenneweg, F., Wang, Y., Jung, M., Mazlan, S., Fiedler, J., Thum, T., Hobuß, L.   +21 more
core   +1 more source

M1 macrophage‐derived exosomes promote autoimmune liver injury by transferring long noncoding RNA H19 to hepatocytes

MedComm, 2023
Exosomes mediate intercellular communication by transmitting active molecules. The function of long noncoding RNA (lncRNA) H19 in autoimmune liver injury is unclear.
Yongting Zhang, Liang Hong, Xuehui Li, Yuyu Li, Xujun Zhang, Jingjing Jiang, Fan Shi, Hongyan Diao   +7 more
doaj   +1 more source

H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase [PDF]

, 2015
DNA methylation is essential for mammalian development and physiology. Here we report that the developmentally regulated H19 lncRNA binds to and inhibits S-adenosylhomocysteine hydrolase (SAHH), the only mammalian enzyme capable of hydrolysing S ...
Men, Yi, Carmichael, Gordon G, Huang, Yingqun, Yang, Lihua, Xie, Juanke, Lu, Lingeng, Zhang, Na, Zhong, Tianyu, Taylor, Hugh S, Chung, Hunter, Zhou, Jichun, Müller, Martin, Giang, Karolyn, Sun, Xueguang   +13 more
core   +2 more sources

RNA-binding Protein LIN28a Regulates New Myocyte Formation in the Heart via lncRNA-H19

, 2023
 Background: Developmental cardiac tissue holds remarkable capacity to regenerate after injury and consists of regenerative mononuclear and diploid cardiomyocytes (MNDCMs).
Jennifer Pennise (14432220), Tej M. Patel (10106364), Tao Wang (12008), Michael Behanan (14432214), Robert C. Hoy (8807582), Vagner Oliveira-Carvalho Rigaud (12706817), Mohsin Khan (352381), Justin Kurian (4459243), Lindsay Kraus (9013847), Isabella Brosious (14432217), Sadia Mohsin (541545), Steven R. Houser (6439097), Clare Zarka (14432211), Jaslyn Johnson (14432223)   +13 more
core   +1 more source

Silencing of the lncRNA H19 enhances sensitivity to X-ray and carbon-ions through the miR-130a-3p /WNK3 signaling axis in NSCLC cells

Cancer Cell International, 2021
Background The lncRNA H19 is believed to act as an oncogene in various types of tumors and is considered to be a therapeutic target and diagnostic marker.
Xueshan Zhao, Xiaodong Jin, Qiuning Zhang, Ruifeng Liu, Hongtao Luo, Zhen Yang, Yichao Geng, Shuangwu Feng, Chengcheng Li, Lina Wang, Xiaohu Wang, Qiang Li   +11 more
doaj   +1 more source