Results 11 to 20 of about 39,827 (164)

The Potential Utility of Circulating Oncofetal H19 Derived miR-675 Expression versus Tissue lncRNA-H19 Expression in Diagnosis and Prognosis of HCC in Egyptian Patients

Biomolecules, 2022
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Interestingly, lncRNA-H19 acts independently in HCC and influences miR-675 expressions.
Shimaa Abdelsattar, Dina Sweed, Hala F. M. Kamel, Zeinab A. Kasemy, Abdallah M. Gameel, Hassan Elzohry, Omnia Ameen, Eman Ibrahim Elgizawy, Ahmed Sallam, Asmaa Mosbeh, Mahmoud S. Abdallah, Fatma O. Khalil, Hiba S. Al-Amodi, Sally M. El-Hefnway   +13 more
doaj   +2 more sources

Relationship between the Levels of lncRNA H19 in Plasma and Different Adipose Tissue Depots with Patients’ Response to Bariatric Surgery

Life, 2022
Bariatric surgery represents a widespread approach to treating morbid obesity. The search for biomarkers to identify patients to whom this type of treatment will be most effective is needed.
Marina S. Artemyeva, Ludmila B. Vasileva, Yi Ma, Kirill A. Kondratov, Anton V. Fedorov, Anna A. Kostareva, Sofia E. Lapshina, Anna D. Anopova, Nikolai P. Likhonosov, Alexander E. Neymark, Alina Yu. Babenko, Evgeny V. Shlyakhto   +11 more
doaj   +2 more sources

Hypomethylation of the LncRNA H19 promoter accelerates osteogenic differentiation of vascular smooth muscle cells by activating the Erk1/2 pathways

Journal of International Medical Research
Objective Vascular calcification is a common chronic kidney disease complication. This study aimed to investigate the function of long non-coding RNA (LncRNA) H19 in vascular calcification to explore new therapeutic strategies.
Taoxia Wang, Meijuan Cheng, Jingjing Jin, Yaling Bai, Dongxue Zhang, Shenglei Zhang, Jinsheng Xu   +6 more
doaj   +2 more sources

Long non-coding RNA H19 promotes cervical cancer development via targeting the microRNA-140/ALDH1A1 axis

European Journal of Medical Research
Background Dysregulation of long non-coding RNA H19 (lncRNA H19) is involved in cervical cancer (CC) progression. This study aims to unveil the specific role and relevant mechanism of lncRNA H19 in CC. Methods The expression of lncRNA H19 in CC cells was
Jie Ming, Fang Cheng, Yating Fu, Meng Zhang, Qian Rou, Kaixiong Liu, Zinati Nuertai, Shanshan Xu, Ling Tao, Alfira Abudujapar, Ying Liu   +10 more
doaj   +2 more sources

Long noncoding RNA H19 is a critical oncogenic driver and contributes to epithelial-mesenchymal transition in papillary thyroid carcinoma

Cancer Management and Research, 2019
Wei-Quan Liang,1,* De Zeng,2,* Chun-Fa Chen,1 Shu-Ming Sun,1 Xiao-Feng Lu,1 Chun-yan Peng,3 Hao-Yu Lin1 1Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515000, People ...
Liang WQ, Zeng D, Chen CF, Sun SM, Lu XF, Peng CY, Lin HY   +6 more
doaj   +1 more source

The lncRNA H19/miR-766-3p/S1PR3 Axis Contributes to the Hyperproliferation of Keratinocytes and Skin Inflammation in Psoriasis via the AKT/mTOR Pathway

Mediators of Inflammation, 2021
Background. The pathogenesis of long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) are well studied in psoriasis. However, little is known about how specific lncRNAs and miRNAs affect the mechanism of psoriasis development and which pathways are ...
Yuexi He, Xiran Yin, Jianjun Yan, Xue Li, Qing Sun   +4 more
doaj   +2 more sources

Extracellular vesicle-mimetic nanovesicles transport LncRNA-H19 as competing endogenous RNA for the treatment of diabetic wounds

Drug Delivery, 2018
Diabetic wounds, one of the most enervating complications of diabetes mellitus, affect millions of people worldwide annually. Vascular insufficiency, caused by hyperglycemia, is one of the primary causes and categories of diabetic impaired wound healing.
Shi-Cong Tao, Bi-Yu Rui, Qi-Yang Wang, Ding Zhou, Yang Zhang, Shang-Chun Guo   +5 more
doaj   +2 more sources

rs217727 of lncRNA H19 is Associated with Cervical Cancer Risk in the Chinese Han Population. [PDF]

Pharmgenomics Pers Med, 2023
Jie Dai,1,* Shao Zhang,2,* Yuhan Shi,3 Jinmei Xu,2 Weipeng Liu,1 Jia Yang,1 Li Shi,1 Zhiling Yan,2,4 Chuanyin Li1 1Department of Immunogenetics, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College ...
Dai J, Zhang S, Shi Y, Xu J, Liu W, Yang J, Shi L, Yan Z, Li C.   +8 more
europepmc   +2 more sources

Resistance to doxorubicin therapy in breast cancer cells could be attenuated by ligustilide: impact on autophagy and LncRNA H19. [PDF]

BMC Complement Med Ther
Background Resistance to DOX in breast cancer (BC) treatment is attributed to multiple mechanisms. The potential of autophagy inhibition in mitigating DOX resistance in BC has yet to be clarified.
Amr EA, El-Feky OA, Khedr EG, El-Ashmawy NE.   +3 more
europepmc   +2 more sources

The Pathogenic Role of Long Non-coding RNA H19 in Atherosclerosis via the miR-146a-5p/ANGPTL4 Pathway

Frontiers in Cardiovascular Medicine, 2021
The abnormally expressed long non-coding RNA (lncRNA) H19 has a crucial function in the development and progression of cardiovascular disease; however, its role in atherosclerosis is yet to be known.
Shi-Feng Huang, Guifang Zhao, Xiao-Fei Peng, Wen-Chu Ye   +3 more
doaj   +1 more source