Construction of TF-lncRNA-miRNA-mRNA Regulatory Network Affecting Sow Reproduction Based on QTLs for Corpus Luteum Number. [PDF]
Wang M +6 more
europepmc +1 more source
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source
RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li +3 more
wiley +1 more source
PTBP1 controls miRNA loading on target RNAs: lessons from the CyCoNP lncRNA. [PDF]
Grazzi A, Desideri F, Bozzoni I.
europepmc +1 more source
Cross‐Level Regulatory Interactions Underlying Human Immune Aging
We performed multi‐omics sequencing on peripheral blood samples from 69 individuals aged 23–75 years and identified multi‐layered molecular interaction networks underlying the process of immune senescence, which provides a comprehensive multi‐omics framework for understanding immune aging and identifying potential strategies to delay immunosenescence ...
Quanyou Wu +9 more
wiley +1 more source
Long Non-Coding RNAs in Pathogenesis of Renal Cell Carcinoma: Epigenetic Regulation, Signaling Pathways, and Therapeutic Strategies. [PDF]
Savelieva O +4 more
europepmc +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Improved RNA-DNA interaction calling suggests RNA-based gene regulation of phenotypic transitions. [PDF]
Zehr S +9 more
europepmc +1 more source
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He +2 more
wiley +1 more source
Long non-coding RNA transcripts in crucian carp brain - annotation and expression patterns in anoxia and reoxygenation. [PDF]
Winklhofer M, Nilsson GE, Lefevre S.
europepmc +1 more source

