What's new? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt +6 more
wiley +1 more source
Long Non-Coding RNAs in Human Disease: An Overview of Biogenesis, Molecular Mechanism and Therapeutic Opportunities. [PDF]
Dubey AK, Kumar A, Nurbekova Z, Kumar N.
europepmc +1 more source
Influence of MC1R Gene Variants on Coat Color of Indicine Cattle Breeds
ABSTRACT Indicine cattle display a broad range of coat colors, representing a relevant and breed‐defining trait required for registration in breeder association. Among the genes involved in pigmentation, MC1R stands out for modulating the synthesis of melanin‐related proteins and remains poorly explored in indicine cattle breeds. Therefore, we aimed to
Silel V. S. A. Maciel +12 more
wiley +1 more source
Circular and Long Non-Coding RNAs in Cancer Metabolism: Dual Perspective of Biomarkers and Therapeutic Targets. [PDF]
Carbone FP, Hanau S, Bianchi N.
europepmc +1 more source
Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu +6 more
wiley +1 more source
Insight into the emerging role of long non-coding RNAs in BRAF inhibitor resistance in melanoma. [PDF]
Yadav V +4 more
europepmc +1 more source
ABSTRACT Background Chronic obstructive pulmonary disease (COPD) is associated with musculoskeletal comorbidities, including cachexia. Weight loss (WL) is the major criterion for cachexia and increases risk for mortality in COPD. Risk factors for WL in COPD are incompletely understood.
Joe W. Chiles III +23 more
wiley +1 more source
An explainable-AI framework reveals novel lncRNAs specific for breast cancer subtypes. [PDF]
Patel JC, Veerappa A, Guda C.
europepmc +1 more source
Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang +12 more
wiley +1 more source
Transcriptomic Profiling Identifies TALAM1 and LINC00702 as HIV-1-Responsive lncRNAs in Microglia. [PDF]
Rojas-Celis V +11 more
europepmc +1 more source

