Results 221 to 230 of about 65,339 (267)

LncRNA NEAT1 promotes immunosuppression in gastric cancer under endoplasmic reticulum stress by maintaining the M⁶A methylation of SEMA3A in CAFs. [PDF]

Mol Cancer
Xu Y, Xu R, Chen Z, Zhou H, Liao J, Ji K, Yang S, Zhong X, Li Y, Xi D, Zhang Q, Zhao L, Zuo Q.   +12 more
europepmc   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong, Jieni Li, Mingxuan Pan, Xiaoxue Ke, Hongjuan Cui   +4 more
wiley   +1 more source

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu, Kaifeng Niu, Qingran Kong, Shaorong Gao   +3 more
wiley   +1 more source

Integrated WGCNA of lncRNA-mRNA Networks Identifies Novel Hub Genes and Potential Therapeutic Agents for Liver Cirrhosis via Molecular Docking Validation. [PDF]

Int J Mol Sci
Wu T, Jin J, Yang Y, Sui J, Zhou Y, Yuan H.   +5 more
europepmc   +1 more source

Transcriptome assemblies for two drug‐type cannabis chemotypes by long‐read RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Cannabis sativa has undergone over 10,000 years of domestication, resulting in extensive genetic and phenotypic diversity among cultivated chemotypes. Increased medical and recreational use of specialized metabolites accumulating in cannabis glandular trichomes—primarily the cannabinoids ∆9‐tetrahydrocannabinol (THC) and cannabidiol (CBD)—has ...
Oliver Berkowitz, Ricarda Jost, Sophia Ng, Antony Bacic, James Whelan, Mathew G. Lewsey   +5 more
wiley   +1 more source

Long non-coding RNAs in the exosomal network: dual roles and clinical implications in cancer. [PDF]

Anim Cells Syst (Seoul)
Yoon G, Cho S, Choi YR, Roh J, Kim W.
europepmc   +1 more source

Single‐Cell Sequencing Reveals That CCL2+ Adipose‐Derived Stem Cells Promote Diabetic Wound Healing Through the CCL2‐ACKR1 Signaling Axis

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
scRNA‐seq of human adipose and diabetic wounds revealed a CCL2+ ADSC subpopulation with high stemness and ECM‐enriched pathways. These cells serve as a signaling hub via TGFB1‐TGFBR1, IL34‐CSF1R, and CCL2‐ACKR1. Their exosomes (CCL2‐Exos), carrying CCL2, TGFB1, and IL34, accelerate diabetic wound healing in mice by promoting angiogenesis, collagen ...
Songyun Zhao, Wanying Chen, Kaibo Liu, Jiaheng Xie, Yanming Chen, Hao Dai, Zhongqiu Lu, Longwang Chen, Yucang He, Hua Yu, Liqun Li   +10 more
wiley   +1 more source

Research progress on long non‑coding RNAs in lung cancer (Review). [PDF]

Mol Med Rep
Pan R, Wang C, Tang Y, Zhong F, Zhuang Y, Zhao Q.   +5 more
europepmc   +1 more source

Long Non-Coding RNA-Derived Peptides as a Novel Source of Tumor Neoantigens: Expanding the Immunopeptidome Beyond Canonical Coding Regions. [PDF]

Biology (Basel)
López-Calvo I, Bao-Camacho I, Martín-Revuelta S, Rey-Souto C, Franco-Gacio A, Pérez-Martínez JM, Sandino-Somoza I, Mourenza Á, Rodríguez-Belmonte E, Lamas-Maceiras M, Cerdán ME, Barreiro-Alonso A, Vizoso-Vázquez Á.   +12 more
europepmc   +1 more source

Integrated bioinformatics and experimental validation identify aging-related prognostic genes in clear cell renal cell carcinoma. [PDF]

Medicine (Baltimore)
Liu C, Shuang W, Cao X, Gao Y.
europepmc   +1 more source