Results 231 to 240 of about 752,944 (283)
The role of long non-coding RNAs and circular RNAs in immune evasion of influenza A virus: recent advances. [PDF]
Ju Y, Li Y, Zhou C, Yu X.
europepmc +1 more source
Transient Cyclic Structured Oligonucleotide Designs for Therapeutic Applications
Abstract Oligonucleotide‐based therapeutics are now widely used in clinical settings. From the late 1980s to the mid‐1990s, efforts to improve therapeutic efficacy focused on imparting drug‐like properties to oligonucleotides, emphasizing nuclease stability and target sequence affinity.
Sudhir Agrawal
wiley +1 more source
Noncoding RNAs, Vital Players in Breast Cancer Metastasis. [PDF]
Kang Y +5 more
europepmc +1 more source
Epitranscriptomics as a Candidate Universal Modulator of Dormancy Transitions
Dormancy is presented as a conserved, reversible survival program in which epitranscriptomic RNA modifications are proposed to provide a rapid, energy‐efficient layer that establishes, maintains, and terminates the state by modulating mRNA stability, translation, and localization.
Ehsan Pashay Ahi
wiley +1 more source
Transcriptomic Profiling of mRNA and lncRNA During the Developmental Transition from Spores to Mycelia in <i>Penicillium digitatum</i>. [PDF]
Zhou T +8 more
europepmc +1 more source
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu +6 more
wiley +1 more source
Targeting Pan-Cancer Stemness: Core Regulatory lncRNAs as Novel Therapeutic Vulnerabilities. [PDF]
Deng S, Yang Y, Gao D, Gao J, Xiong Y.
europepmc +1 more source
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao +6 more
wiley +1 more source
Mechanism of LncRNA NORAD regulating ferroptosis in endometrial cancer cells by modifying GPX4 through FTO-mediated m6A methylation. [PDF]
Ke J +5 more
europepmc +1 more source

