Results 151 to 160 of about 167,789 (348)

LncRNA–Protein Interactions: A Key to Deciphering LncRNA Mechanisms

Biomolecules
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators in a multitude of biological processes. However, their functional basis, particularly structure-based functional characteristics, remains elusive. lncRNAs exert their influence primarily through intricate interactions with various cellular components.
Zuoneng Wang, Muhammad Aftab, Zigang Dong, Yanan Jiang, Kangdong Liu   +4 more
openaire   +2 more sources

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

A Testis-Specific Long Non-Coding RNA, lncRNA-Tcam1, Regulates Immune-Related Genes in Mouse Male Germ Cells [PDF]

, 2017
Misuzu Kurihara, Kai Otsuka, Shin Matsubara, Akira Shiraishi, Honoo Satake, Atsushi P. Kimura   +5 more
openalex   +1 more source

Construction of m6A-Related lncRNA Prognostic Signature Model and Immunomodulatory Effect in Glioblastoma Multiforme

, 2022
Pan Xie, Han Yan, Ying Gao, Xi Li, Dongbo Zhou, Zhaoqian Liu   +5 more
openalex   +1 more source

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou, Hao Jiang, Jingsheng Ruan, Daifeng Yang, Xing Chen, Shanshan Cai, Xinglin Yi   +6 more
wiley   +1 more source

Cuproptosis-related lncRNA predicts prognosis and immune pathways in osteosarcoma patients

Guangxi Yike Daxue xuebao
Objective To identify cuproptosis-related lncRNAs (CRLs) and use them to construct models to predict survival in osteosarcoma (OS) patients. Methods RNA-seq data of OS patients were downloaded from the TARGET database along with relevant clinical ...
LIAO Jun, FENG Yanbin, XI Deshuang, ZONG Shaohui   +3 more
doaj   +1 more source

lncRNA ZEB1-AS1 promotes pulmonary fibrosis through ZEB1-mediated epithelial–mesenchymal transition by competitively binding miR-141-3p [PDF]

, 2019
Weibin Qian, Xinrui Cai, Qiuhai Qian, Wei Peng, Jie Yu, Xinying Zhang, Li Tian, Can Wang   +7 more
openalex   +1 more source

The role of miRNA, lncRNA and circRNA in the development of intervertebral disk degeneration (Review)

, 2021
Jian Fa Jiang, Yuefeng Sun, Gaoran Xu, Hong Wang, Ling Wang   +4 more
openalex   +2 more sources

Human Breast Milk‐Derived Exosomal FP671120.4 Inhibits Macrophage M1 Polarization via Modulating the ELAVL1/Nrf2 Axis in Sepsis‐Associated Liver Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐associated liver injury (SALI) plays a major role in aggravating disease progression and worsening prognosis in patients with sepsis. Macrophage polarization is a key factor in the modulation of SALI progression. Recent studies have shown that human breast milk‐derived exosomes (HBM‐Exos) regulate processes involved in macrophage ...
Zhao‐Bin Yang, Yi‐Bin Gao, Xiao‐Mei Cheng, Lu‐Zhen Qiu   +3 more
wiley   +1 more source

An exosome-related lncRNA signature correlates with prognosis, immune microenvironment, and therapeutic responses in hepatocellular carcinoma

, 2023
Peng Wang, Shuya Bai, Mengli Zheng, Wei Chen, Yanlin Li, Yilei Yang, Yuchong Zhao, Si Xiong, Ronghua Wang, Bin Cheng   +9 more
openalex   +1 more source