Results 151 to 160 of about 103,530 (319)

LncRNA-disease association prediction method based on heterogeneous information completion and convolutional neural network [PDF]

arXiv
The emerging research shows that lncRNA has crucial research value in a series of complex human diseases. Therefore, the accurate identification of lncRNA-disease associations (LDAs) is very important for the warning and treatment of diseases. However, most of the existing methods have limitations in identifying nonlinear LDAs, and it remains a huge ...
arxiv  

The lncRNA PCAT29 Inhibits Oncogenic Phenotypes in Prostate Cancer [PDF]

, 2014
Rohit Malik, Lalit R. Patel, John R. Prensner, Yang Shi, Matthew K. Iyer, Shruthi Subramaniyan, Alexander Carley, Yashar S. Niknafs, Anirban Sahu, Sumin Han, Teng Ma, Meilan Liu, Irfan A. Asangani, Xiaojun Jing, Xuhong Cao, Saravana M. Dhanasekaran, Dan R. Robinson, Felix Y. Feng, Arul M. Chinnaiyan   +18 more
openalex   +1 more source

Exploring the Potentials and Challenges of Using Large Language Models for the Analysis of Transcriptional Regulation of Long Non-coding RNAs [PDF]

arXiv
Research on long non-coding RNAs (lncRNAs) has garnered significant attention due to their critical roles in gene regulation and disease mechanisms. However, the complexity and diversity of lncRNA sequences, along with the limited knowledge of their functional mechanisms and the regulation of their expressions, pose significant challenges to lncRNA ...
arxiv  

TF2LncRNA: Identifying Common Transcription Factors for a List of lncRNA Genes from ChIP-Seq Data [PDF]

, 2014
Qinghua Jiang, Jixuan Wang, Yadong Wang, Rui Ma, Xiaoliang Wu, Yu Li   +5 more
openalex   +1 more source

LncRNAs in Inflammation

JACC: Basic to Translational Science, 2022
David A. Salisbury, Aneesh Kallapur, Giuliana G. Repetti, Josue Fraga, Jason Kim, Xiaohui Wu, Tamer Sallam   +6 more
openaire   +2 more sources

Breaking barriers: Smart vaccine platforms for cancer immunomodulation

Cancer Communications, EarlyView.
Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari, Taha Ghantabpour, Nima Pourgholam, Neda Rostami, Stephen M. Hatfield, Farzaneh Namazifar, Shadi Abkhiz, Seyed Sadegh Eslami, Mahsa Ramezanpour, Mahsa Darestanifarahani, Igor Astsaturov, Sidi A. Bencherif    +11 more
wiley   +1 more source

Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan, Jinling Song, Yuqing Ren, Yuyuan Zhang, Yuhao Ba, Peng Luo, Quan Cheng, Hui Xu, Siyuan Weng, Anning Zuo, Shutong Liu, Xinwei Han, Jinhai Deng, Zaoqu Liu   +13 more
wiley   +1 more source

3plex Web: An Interactive Platform for RNA:DNA Triplex Prediction and Analysis [PDF]

arXiv
Summary: Long non-coding RNAs (lncRNAs) exert their functions by cooperating with other molecules including proteins and DNA. Triplexes, formed through the interaction between a single-stranded RNA (ssRNA) and a double-stranded DNA (dsDNA), have been consistently described as a mechanism that allows lncRNAs to target specific genomic sequences in vivo.
arxiv  

Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility [PDF]

, 2014
Timothy J. Pullen, Guy A. Rutter
openalex   +1 more source

Role of lncRNAs in health and disease--size and shape matter [PDF]

, 2014
Vikrant Mohanty, Yesim Gökmen–Polar, Sunil Badve, Sarath Chandra Janga   +3 more
openalex   +1 more source