Results 341 to 350 of about 215,538 (386)

The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population‐based cohort study

International Journal of Cancer, Volume 157, Issue 8, Page 1746-1755, 15 October 2025.
What's New? Patients with stage II colon cancer exhibit considerable variation in prognosis. Consequently, decisions regarding the necessity of adjuvant chemotherapy in this population often rely on imperfect high‐risk criteria. Here, the authors developed a novel RNA‐based risk score, using NanoString nCounter technology, to stratify recurrence risk ...
Ulrik Korsgaard, Maria P. Kristensen, Juan L. García‐Rodríguez, Sanne Kjær‐Frifeldt, Jan Lindebjerg, Torben F. Hansen, Jørgen Kjems, Henrik Hager, Lasse S. Kristensen   +8 more
wiley   +1 more source

Role of autophagy‑modulating long non‑coding RNAs in tumor radioresistance (Review). [PDF]

Oncol Rep
Li H, He Z.
europepmc   +1 more source

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

International Journal of Cancer, Volume 157, Issue 8, Page 1519-1537, 15 October 2025.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li, Yijin Yu, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao   +7 more
wiley   +1 more source

RNA sequencing of the lncRNA regulome modulated by Withania somnifera in human neuroblastoma SK-N-SH cells. [PDF]

Mol Biol Rep
Sharma E, Mehta D, Sahare S, Ajgaonkar S, Saha P, Bhaskar A, Trivedi J, S D, Moorthy M, Ramaswamy G, Nair S.   +10 more
europepmc   +1 more source

A Novel C19orf47‐AKT2 Chimeric RNA Generated by Cis‐Splicing of Adjacent Genes Is Associated With Glioblastoma Prognosis

Annals of Clinical and Translational Neurology, Volume 12, Issue 10, Page 2116-2129, October 2025.
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang, Bowen Ni, Kezhi Wu, Qi Zhang, Jinglin Guo, Runwei Yang, Ziyu Wang, Guozhong Yi, Guanglong Huang, Minyi He, Yimin Xu, Yawei Liu   +11 more
wiley   +1 more source

Long non-coding RNAs promote colorectal cancer development through other epigenetic modifications. [PDF]

Gastroenterol Rep (Oxf)
Wang G, Ma Q, Zhu N, Yan Y, Zhong C, Hong X, Lai Y, Chen X, Li N, Yu W.   +9 more
europepmc   +1 more source

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

Advanced Therapeutics, Volume 8, Issue 10, October 2025.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam, Lu Yanjun, Bee Luan Khoo, Tongxu Si, Heng Zou, Mengsu Yang   +5 more
wiley   +1 more source

Epigenetic modification of cuproptosis by non-coding RNAs in cancer drug resistance. [PDF]

Mol Cancer
Du F, Tang L, Wang F, Jiang X, Li J, Wang G, Zhang Z.   +6 more
europepmc   +1 more source

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, Volume 12, Issue 38, October 13, 2025.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

Approaches for Identifying LncRNA-Associated Proteins for Therapeutic Targets and Cancer Biomarker Discovery. [PDF]

Targets (Basel)
Hussain MS, Vij P, Kotnala S, Ahmad S, Chauhan SC, Tripathi MK.   +5 more
europepmc   +1 more source