Results 101 to 110 of about 39,827 (164)

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

Nature Communications, 2018
LncRNA H19 has been shown to be aberrantly expressed in different cancers. Here, the authors show that H19 lncRNA is downregulated in pituitary adenomas and H19 is able to impede pituitary tumorigenesis via disruption of 4E-BPB1 and Raptor interaction to
Ze Rui Wu, Lichong Yan, Yan Ting Liu, Lei Cao, Yu Hang Guo, Yong Zhang, Hong Yao, Lin Cai, Han Bing Shang, Wei Wei Rui, Gang Yang, Xiao Biao Zhang, Hao Tang, Yu Wang, Jin Yan Huang, Yong Xu Wei, Wei Guo Zhao, Bing Su, Zhe Bao Wu   +18 more
doaj   +1 more source

NKX2-1 gene is targeted by H19 lncRNA and is found to be overexpressed in benign nodular goiter tissues

Objective: Nodular goiter may increase the risk of thyroid cancer, but the genetic factors contributing to nodular goiter are not well understood. There is an overexpression of H19 lncRNA in goiter tissue and its target remains unknown. In this study, we
Seyed-Morteza Javadirad
core   +1 more source

Levonorgestrel Ameliorates Adenomyosis via lncRNA H19/miR-17/TLR4 Pathway

Drug Design, Development and Therapy, 2020
Na Liang,1,* Wenfeng Zhang,2,* Hongjiang Wang,3 Wei Shi,4 Li Wang,2 Lijuan Ma2 1Department of Traditional Chinese Medicine, The First Affiliated Hospital of Shandong First Medical University, Shandong Provincial Qianfoshan Hospital, Shandong University ...
Liang N, Zhang W, Wang H, Shi W, Wang L, Ma L   +5 more
doaj  

H19 lncRNA regulates keratinocyte differentiation by targeting miR-130b-3p

, 2017
Aberrant differentiation of keratinocytes has been demonstrated to be associated with a number of skin diseases. A growing number of studies have showed that long noncoding RNAs (lncRNAs) have an important part in gene regulation, however, the role of ...
Zhi-rong Yao, Hong Yu, Lin-ting Huang, Chun-xiao Li, Jian-yin Liang, Hua-guo Li, Yu-wei Kong, Fu-ying Chen   +7 more
core   +1 more source

Transplantation of engineered endothelial progenitor cells with H19 overexpression promotes arterial reendothelialization and inhibits neointimal hyperplasia

Journal of Tissue Engineering
Endothelial injury is a key factor initiating in-stent restenosis (ISR) following peripheral artery stent implantation. Genetically modified endothelial progenitor cells (EPCs) can promote reendothelialization of injured arteries and inhibit neointimal ...
Yanchen Ye, Lin Huang, Kangjie Wang, Yunhao Sun, Zhihao Zhou, Tang Deng, Yunyan Liu, Rui Wang, Ridong Wu, Chen Yao   +9 more
doaj   +1 more source

LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy

, 2018
Background Astrocyte and microglia activation are well-known features of temporal lobe epilepsy that may contribute to epileptogenesis. However, the mechanisms underlying glia activation are not well understood.
Yun-Peng Liu, Ning Chen, Fan-Gang Meng, Ming Ge, Jian-Guo Zhang, Wei Hu, Chun-Lei Han, Liang Li, Xue-Min Zhao, Kai-Liang Wang, Wen-Jia Meng   +10 more
core   +1 more source

LncRNA H19 drives atherosclerosis progression via the miR-let-7a/ITGB3 axis. [PDF]

Front Physiol
Hu ZY, Li Y, Liu LY, Chen XY, Lin KX, Chaurembo AI, Li XS, Huang GQ, Wu XQ, Huang ZF, Xing N, Lin HB.   +11 more
europepmc   +1 more source

Progesterone receptor, prokineticin 1, LncRNA-H19, and miR-210 in molecular regulation of recurrent implantation failure. [PDF]

Sci Rep
Rostami R, Jahanbakhsh J, Salehi S, Asgari K, Fallah S.   +4 more
europepmc   +1 more source

LncRNA H19 as a key regulator in biliary atresia: insights into pathogenesis and potential therapeutic targets. [PDF]

Ann Med
Zhao Q, He F, Zhang Z, Chen L.
europepmc   +1 more source

Non-canonical ceRNA-independent mechanism of the lncRNA-H19/miR-212-5p axis targeting KLF4 in Hcy-triggered VSMCs dysfunction and atherogenesis. [PDF]

Sci Rep
Ma X, Zhang X, Yan Y, Mo T, Ma X, Wang X, Zhang M.   +6 more
europepmc   +1 more source