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LncRNAs and Available Databases
2021Long noncoding RNAs (lncRNAs) are involved in many regulatory mechanisms in practically every step of the RNA cycle, from transcription to RNA stability and translation. They are a highly heterogeneous class of molecules in terms of site of production, interaction networks, and functions. More and more databases are available on the web with the aim to
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Bone, 2020
Bone is a rigid and dynamic organ that continuously undergoes remodeling and repair. The balance between osteoblastic bone formation and osteoclastic bone resorption is essential for normal bone homeostasis. Osteoclasts are giant multinucleated cells derived from the monocyte/macrophage hematopoietic lineage and are regulated by various cytokines. Long
Yongyun Chang +5 more
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Bone is a rigid and dynamic organ that continuously undergoes remodeling and repair. The balance between osteoblastic bone formation and osteoclastic bone resorption is essential for normal bone homeostasis. Osteoclasts are giant multinucleated cells derived from the monocyte/macrophage hematopoietic lineage and are regulated by various cytokines. Long
Yongyun Chang +5 more
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LncRNA MALAT1 Promotes Ulcerative Colitis by Upregulating lncRNA ANRIL
Digestive Diseases and Sciences, 2020LncRNA MALAT1 contributes to the inflammatory responses induced by lipopolysaccharides (LPS), which shares similar pathogenesis with ulcerative colitis (UC), indicating the potential involvement of MALAT1 in UC.Expression of MALAT1 and lncRNA ANRIL in both UC patients and healthy controls was analyzed by RT-qPCR. ROC curve analysis was used to evaluate
Mingyan Zhu, Jian Xie
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WIREs RNA, 2016
The diversity of long non‐coding RNAs (lncRNAs) in the human transcriptome is in stark contrast to the sparse exploration of their functions concomitant with their conservation and evolution. The pervasive transcription of the largely non‐coding human genome makes the evolutionary age and conservation patterns of lncRNAs to a topic of interest.
Anne Nitsche, Peter F. Stadler
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The diversity of long non‐coding RNAs (lncRNAs) in the human transcriptome is in stark contrast to the sparse exploration of their functions concomitant with their conservation and evolution. The pervasive transcription of the largely non‐coding human genome makes the evolutionary age and conservation patterns of lncRNAs to a topic of interest.
Anne Nitsche, Peter F. Stadler
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Science Signaling, 2015
The interaction of a lncRNA with the complex of NF-κB and its inhibitor IκB prevents phosphorylation-mediated release and activation of NF-κB.
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The interaction of a lncRNA with the complex of NF-κB and its inhibitor IκB prevents phosphorylation-mediated release and activation of NF-κB.
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The Functions and Unique Features of LncRNAs in Cancer Development and Tumorigenesis
International Journal of Molecular Sciences, 2021Kenzui Taniue, Nobuyoshi Akimitsu
exaly
MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma
Genes and Diseases, 2021Fengxia Gao, Sirong He, Aishun Jin
exaly