Results 41 to 50 of about 402,825 (307)

Improved transducer for squeeze-film bearings [PDF]

open access: yes, 1971
Transducer amplifies vibrations produced by piezoelectric drivers, creating greater amplitudes than were possible with direct drive devices. Drivers isolated from bearing surfaces result in bearings with high axial load capacity and stiffness, thus, wear
Hoogenbloom, L.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

载荷和几何参数对单排四点接触球轴承载荷分布的影响

open access: yesJixie chuandong, 2013
The load distribution analysis is the foundation of carrying load capacity analysis, the drawing of static carrying load capacity curve, designing and selecting of slewing bearing.
张黎燕   +3 more
doaj  

Numerical Study on the Effects of Helix Diameter and Spacing on the Helical Pile Axial Bearing Capacity in Cohesionless Soils

open access: yesJournal of the Civil Engineering Forum
The methods employed to calculate the axial bearing capacity of a helical pile depends on the shear failure model around the pile, which is also influenced by the spacing and diameter of the helical plates.
Ignatius Tommy Pratama   +2 more
doaj   +1 more source

Practical reliability-based calculation tool for the post-fire assessment of concrete beams [PDF]

open access: yes, 2015
If a structure has been able to maintain stability during fire exposure, the residual load-bearing capacity of the structural elements after fire should be determined when deciding upon the further use of the structure. Since adequate safety is a primary
Caspeele, Robby   +2 more
core   +1 more source

Capacity of grillage foundations under horizontal loading [PDF]

open access: yes, 2012
Grillage foundations are an alternative to solid surface mudmats for supporting seabed infrastructure, offering improved hydrodynamic performance and savings in foundation material.
Bransby, M. F.   +10 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Experimental Study of a Strip Footing under Inclined and Eccentric Load on Geogrid Reinforced Sandy Soil

open access: yesTikrit Journal of Engineering Sciences, 2017
This study investigates the "bearing capacity" of a strip footing subjected to inclined and"eccentric load" on geogrid reinforced sandy soil by using physical modeling.
Jawdat K. Abbas, Mohammed A. Al-Zandi
doaj   +3 more sources

Evaluation of axial load-bearing capacity of concrete columns strengthened by a new section enlargement method

open access: yesJournal of Civil Engineering and Management, 2021
The objective of this study is to evaluate the axial load-bearing capacity of section-enlargement concrete columns. To reach the objection, a new strengthened method in which columns are jacketed with a large welded octagonal stirrup at the center and ...
Meijing Hao, Wenzhong Zheng, Wei Chang
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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