Results 71 to 80 of about 402,825 (307)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Experimental and Numerical Investigation on the Ultimate Bearing Capacity of Axially Compressed Steel Tube Columns with Local Corrosion

Buildings
In this paper, 17 types of circular, hollow steel tube columns were designed for the axial compression test. A defect was corroded with an acid rain spray method.
Wei Fang, Tao Wang, Mengcheng Chen, Mingyang Zhang, Hong Huang, Kaicheng Xu, Qingqing Wen   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Study on increasing load capacity of wooden arch bridge by CFRP strengthening: experimental and numerical Verification

Frontiers in Materials
The wooden arch corridor bridge is a typical representative of Chinese wooden bridges, holding significant historical research value. Currently, these bridges face issues of severe component deformation and insufficient load-bearing capacity.
Liping Li, Yan Wang, Yafei Zhang, Xu Wang, Guangyao Ji, Xuping Li   +5 more
doaj   +1 more source

Analysis of Spherical Texture On Characteristics of Hydrodynamic Journal Beraing [PDF]

, 2015
Texture produced on the surface of hydrodynamic journal bearing have certain changes in the coefficient of friction, load carrying capacity, wear rate, stiffness and damping of the two surfaces which are matting with each other.
Dawani, Himalaya
core  

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Korelasi antara Nilai CBR dan Nilai Kuat Geser sebagai Tanah Timbun [PDF]

, 2014
In constructing the roadway, subgrade is the important part to supporting the whole traffic load/construction load above. The bearing capacity of subgrade influences the flexible pavement, if bearing capacity is higher, then the application of flexible ...
Albajili, F. (Farian), Fatnanta, F. (Ferry), Nugroho, S. A. (Soewignyo)   +2 more
core  

Behavior of axially loaded circular stainless steel tube confined concrete stub columns [PDF]

, 2019
A stainless steel tube confined concrete (SSTCC) stub column is a new form of steel-concrete composite column in which the stainless steel tube without bearing the axial load directly is used to confine the core concrete.
Fu, F., Guo, L., Huang, H., Liu, Y.
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source