Results 91 to 100 of about 1,160,595 (297)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Novel Control Scheme for Load Frequency Control

open access: yesMajlesi Journal of Electrical Engineering
In this paper, a hybrid of Neural Network (NN) and Fast Traversal Filter (FTF) based controller is used to determine the optimal parameters of Load Frequency Control (LFC) of a realistic two area power system.
Monika Gupta   +2 more
doaj  

Load Frequency Control for Multi Area Smart Grid based on Advanced Control Techniques

open access: yesAlexandria Engineering Journal, 2018
One of the main interested subjects in electric power systems is the integration of electric vehicles to the existing power network as well as the influence of this integration with the other types of renewable sources connected to the multi area power ...
Mohamed M. Ismail, Ahmed F. Bendary
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

CPLD based controller for single phase inverters [PDF]

open access: yes, 2007
The DC-AC converter, also known as inverter, converts DC power to AC power at desired output voltage and frequency. The DC power input to the inverter is obtained from an existing power supply.
Saiman, Suhaimi
core  

Adaptive Event-Triggered Load Frequency Control for Interconnected Microgrids by Observer-Based Sliding Mode Control

open access: yesIEEE Access, 2019
This paper focuses on the load frequency control (LFC) for a multi-area interconnected microgrid power system with the introduction of communication networks, a robust sliding mode control strategy based on the adaptive event-triggered mechanism is ...
Hongyue Li, Xihuai Wang, Jianmei Xiao
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Fast control technique for high frequency (5MHz) DC/DC integrated converter [PDF]

open access: yes, 2010
A switching frequency of 5 MHz allows the integration in a chip of a low power (10W) DC/DC converter. Although this switching frequency would make feasible a voltage mode control with 1MHz bandwidth, the parasitics and robustness don't allow such a high ...
Alou Cervera, Pedro   +4 more
core  

Distributed Optimal Frequency Control Considering a Nonlinear Network-Preserving Model

open access: yes, 2018
This paper addresses the distributed optimal frequency control of power systems considering a network-preserving model with nonlinear power flows and excitation voltage dynamics. Salient features of the proposed distributed control strategy are fourfold:
Liu, Feng   +4 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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