Results 111 to 120 of about 1,670,871 (318)

The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading

open access: gold, 2017
Anna Baulies   +18 more
openalex   +1 more source

Bolted double-lap composite joints under mechanical and thermal loading [PDF]

open access: green, 2001
Vladimir Kradinov   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Thermal behaviour of medium-voltage underground cables under high-load operating conditions

open access: green, 2019
Sergio Bustamante   +6 more
openalex   +2 more sources

HLA-B Signal Peptide Polymorphism Influences the Rate of HIV-1 Acquisition but Not Viral Load [PDF]

open access: bronze, 2012
Aimee Merino   +7 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Analysis of concrete taken from a loaded column by determining the modulus of elasticity

open access: yesActa Polytechnica CTU Proceedings
Sustainability places an emphasis on preserving and using existing structures, particularly those that are historically or artistically valuable. The preservation of buildings is closely related to a good assessment of their condition.
Kristýna Hrabová   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Immediate Loading

open access: yesImplant Dentistry, 2002
William, Chong   +4 more
openaire   +3 more sources

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