Results 91 to 100 of about 2,490,428 (309)

Mathematical modeling of the roller-rope coupling operation in misalignment conditions

Қарағанды университетінің хабаршысы. Математика сериясы, 2018
The article deals with the results of construction and mathematical modeling of rope - roller coupling in condition of radial misalignment. As a result of modeling, the operation of coupling is revealed in the presence of misalignment of the shafts ...
V.А. Protsenko, М.V. Babiy, V.А. Nastasenko   +2 more
doaj   +1 more source

Load-bearing of driving hydro-cylinders.

, 2018
Load-bearing of driving hydro-cylinders.
Lirong Wan (5641868), Kuidong Gao (5641871), Qingliang Zeng (5641862), Yang Yang (45629), Jiehan Zhou (5641865)   +4 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

SSA-BiLSTM Model-Based SOH Estimation for Lithium-Ion Batteries

Energies
The State of Health (SOH) of a battery is an important indicator for measuring the performance degradation of batteries. In view of the deficiencies of existing SOH estimation methods in feature processing and model accuracy, this paper conducts research
Yizeng Wu, Bo Rao, Jie Tian, Jinqiao Du, Jiuchun Jiang   +4 more
doaj   +1 more source

Analyzing the Network Response Time and Load Balancing [PDF]

This paper describes the network response time which represent a significant indicator for network performance and how load balancing can improve the network performance.response time, load balancing, throughput, network ...
Madalina MLAK
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Participation in and use of skills development for work ability and expected retirement age: a cross-sectional study among senior workers

Frontiers in Public Health
IntroductionEurope’s aging population calls for ways to prolong working life. Skills development initiatives could potentially improve work ability and extend working lives and may thus be key to address this challenge.
Karina Glies Vincents Seeberg, Karina Glies Vincents Seeberg, Sebastian Venge Skovlund, Sebastian Venge Skovlund, Emil Sundstrup, Ole Steen Mortensen, Ole Steen Mortensen, Lars Louis Andersen, Lars Louis Andersen   +8 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source