Results 111 to 120 of about 4,509,005 (309)

A global model-agnostic rule-based XAI method based on Parameterized Event Primitives for time series classifiers

Frontiers in Artificial Intelligence
Time series classification is a challenging research area where machine learning and deep learning techniques have shown remarkable performance. However, often, these are seen as black boxes due to their minimal interpretability.
Ephrem Tibebe Mekonnen, Ephrem Tibebe Mekonnen, Luca Longo, Luca Longo, Pierpaolo Dondio   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

RESEARCH OF THE EFFICIENCY OF THE TRAFFIC FLOW MANAGEMENT METHOD BASED ON THE INFORMATION ABOUT THE LOAD OF SOFTWARE-DEFINED NETWORKS

Современная наука и инновации, 2022
This article describes the efficiency problem of the implementation of the traffic flow management method, based on the network nodes load information, used to balance the traffic to the routes with unequal metrics, which is being implemented within the ...
P. A. Isachenkov, A. V. Krasov, M. V. Levin   +2 more
doaj  

Feasibility Study of RFID Technology for Construction Load Tracking [PDF]

, 2010
INE/AUTC 10 ...
Henrie, Morgan, Ronchetti, Mike
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Differences in knee flexor and extensor force and kinematic variables in rural versus urban area female students in Romania

Frontiers in Physiology
The study aimed to identify and explain the typical differences in low-intensity high-volume resistance training (LIHV-RT) performances for major muscle groups between rural versus urban young female students to establish the relevant set of quantitative
Ioana Mădălina Petre, Hadi Nobari, Hadi Nobari, Mircea Boscoianu, Bogdan Pelin, Anca Ionescu, Pablo Prieto González, Rafael Oliveira, Rafael Oliveira, Rafael Oliveira, Bogdan Oancea   +10 more
doaj   +1 more source

Dynamic load balancing algorithm complexity [PDF]

, 1987
This paper presents a theoretical analysis of the asymptotic complexity inherent in a load balancing algorithm in a loosely-coupled network, where processor communication is achieved by message passing.
Cha, Sung D.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source