Results 161 to 170 of about 2,021,406 (318)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
An optimization method for flexible interconnection planning based on improved CNN-LSTM prediction and tunable relative entropy-driven chaotic evolution. [PDF]
PLoS OneZhao X +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Modelling and forecasting short-term electricity load: a two step methodology [PDF]
The goal of this paper is to develop a forecasting model of the hourly electricity load demand in the area covered by an utility company located in the southeast of Brazil.
Lacir J. Soares, Marcelo Cunha Medeiros
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Determine the optimal ignition timing function based on combustion duration, load and fuel blending ratio of an engine powered with diesel-methanol blends. [PDF]
PLoS OneHong TD +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Load Management: Opportunity or Calamity?
, 1981 After the change in the economics of generating electricity which took place in 1973, many utilities are examining options to hold down their costs. One fact which is clear is that the difference between peak and off peak generating costs is much larger ...
Males, R., Hassig, N.
core
The PAPER heuristic: a structured cognitive aid to reduce intrinsic cognitive load in early clinical reasoning training. [PDF]
BMC Med EducGebauer M +4 more
europepmc +1 more source