Results 81 to 90 of about 1,494,355 (294)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

A sliding window-based dynamic load balancing for heterogeneous Hadoop clusters

open access: yes, 2016
At present MapReduce computing model‐based Hadoop framework has gradually become the most famous distributed computing framework because of its remarkable features such as scalability, fault tolerance, data security, and powerful IO ability.
Xiang, Y.   +4 more
core   +1 more source

A Load-Balancing Scheduling Scheme based on Heterogeneous Workloads in Cloud Data Centers

open access: yes工程科学与技术, 2013
:Current approaches to improve the rate of load balance in cloud data centers did not investigate the problem of combining different workload types.
Li Hong-You, Peng Jian
doaj  

Dynamic bandwidth allocation with machine learning in dense WiFi network

open access: yesFACETS
Efficient load balancing is a fundamental aspect within a densely populated Wireless Fidelity (WiFi) network, particularly when the goal is to evenly distribute bandwidth and regulate Internet usage. The distribution of network traffic for load balancing
Ricardo Alvarado   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Reliable load-balancing routing for resource-constrained wireless sensor networks [PDF]

open access: yes, 2012
Wireless sensor networks (WSNs) are energy and resource constrained. Energy limitations make it advantageous to balance radio transmissions across multiple sensor nodes.
Daabaj, Khaled
core  

Dynamic Diffusion Load Balancing [PDF]

open access: yes, 2005
We consider the problem of dynamic load balancing in arbitrary (connected) networks on n nodes. Our load generation model is such that during each round, n tasks are generated on arbitrary nodes, and then (possibly after some balancing) one task is deleted from every non-empty node. Notice that this model fully saturates the resources of the network in
Berenbrink, P.   +2 more
openaire   +3 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy