Results 141 to 150 of about 3,943,525 (296)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Role of dorsal and ventral hippocampus in working memory load capacity.

, 2017
Objectives: The hippocampus (HP) regulates working memory capacity (WMC) in conditions of high memory load (Sannino et al., 2012). Anatomic, genetic and behavioral studies suggested that the HP is subdivided into a dorsal (dHP) and a ventral (vHP ...
Filomena Grazia, Giordano, Nadia Concetta, Carboncino, Anna, Carrella, Diego, Crain, Jennifer, Deleonibu, Elvira, ALVINO, FILOMENA GRAZIA, Olivito, Laura   +8 more
core  

Adolescents with Atopic Dermatitis Have Lower Peak Exercise Load Capacity and Exercise Volume Compared with Unaffected Peers. [PDF]

Int J Environ Res Public Health, 2022
Yang TH, Chen PC, Lin YC, Lee YY, Tseng YH, Chang WH, Chang LS, Lin CH, Kuo HC.   +8 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Load-Capacity-Constrained Arm-Angle Planning for a Centrally Driven Humanoid Robotic Arm. [PDF]

Biomimetics (Basel)
Lu Z, Zhu Z, Chen S, Jiang T, Luo Z.
europepmc   +1 more source

A Roadmap toward Achieving Sustainable Environment: Evaluating the Impact of Technological Innovation and Globalization on Load Capacity Factor. [PDF]

Int J Environ Res Public Health, 2022
Awosusi AA, Kutlay K, Altuntaş M, Khodjiev B, Agyekum EB, Shouran M, Elgbaily M, Kamel S.   +7 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Competitive Electricity Markets and Investment in New Generating Capacity [PDF]

Evidence from the U.S. and some other countries indicates that organized wholesale markets for electrical energy and operating reserves do not provide adequate incentives to stimulate the proper quantity or mix of generating capacity consistent with ...
Joskow, Paul L.
core  

Artificial intelligence and environmental sustainability: a nonlinear analysis of the load capacity factor in OECD countries. [PDF]

Sci Rep
Luo H, Zhang L, Sun Y, Zhang L.
europepmc   +1 more source

A critical analysis of research methods and experimental models to study the load capacity and clinical behaviour of the root filled teeth. [PDF]

Int Endod J, 2022
Ordinola-Zapata R, Lin F, Nagarkar S, Perdigão J.   +3 more
europepmc   +1 more source