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Results 161 to 170 of about 1,598,056 (300)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source

Sustainable development beyond emissions: the role of ICT, load capacity factor, green technology patents, and energy transition in OECD countries. [PDF]

Sci Rep
Demirtas N +5 more
europepmc +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

Lateral load capacity of flexible piles in the SDMC model with cylindrical cavity expansion theory. [PDF]

Sci Rep
Gao F, Hu C, Huang B, Pang L.
europepmc +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano +2 more
wiley +1 more source

Shaping Somalia's environmental sustainability: the role of institutional quality, renewable energy, economic growth, and financial globalization on load capacity factor. [PDF]

Sci Rep
Daror HO, Warsame AA, Ahmed Z.
europepmc +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source

Machine learning-based prediction of the axial load capacity of UHPC strengthened reinforced concrete columns: A comparative analysis. [PDF]

PLoS One
Hoang VH, Tran MQ, Ngo VT.
europepmc +1 more source

DETERMINATION OF LOADED GEAR FLEXIBLE TRANSMISSION LOAD CAPACITY

Dynamics of Systems, Mechanisms and Machines, 2018
A. N. Abakumov, N. V. Zaharova
openaire +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source