Results 91 to 100 of about 6,077,856 (315)

Performance Analysis and Flow Mechanism of Close-Range Overlapping Rotor in Hover

open access: yesDrones
High payload capacity multi-rotor aerial vehicles are typically configured with multiple propellers to achieve the required aerodynamic lift. However, this design approach often results in an increased overall dimensional envelope, which introduces ...
Ziyi Xu   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Simplified Load Distribution Factors for Fiber Reinforced Polymer Composite Bridge Decks

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2013
In recent years, researchers have investigated the load distribution factors due to vehicle wheel loads. Several load distribution factors for fiber reinforced polymer deck-steel stringer bridge systems have been proposed.
Woraphot Prachasaree   +3 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Energy-Saving Optimization Strategy Research for Chilled Water Units Based on Active Water Storage

open access: yesZhileng xuebao
An energy-saving optimization operation strategy based on maintaining the high-energy-efficiency operation of chillers is proposed to address the prevalent issue of increased energy consumption in the application of cold-storage technology for economic ...
Huang Junjie   +5 more
doaj  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Three‐and‐a‐Half‐Year Follow‐Up After Sacroiliac Joint Fusion With Preexisting Ipsilateral Total Hip Arthroplasty: A Case Report

open access: yesClinical Case Reports
Sacroiliac joint fusion was performed in a patient with a preexisting ipsilateral total hip arthroplasty, with no hip dislocation and unrestricted return to farm work at 3.5 years.
Dustin J. Kress   +4 more
doaj   +1 more source

Deep learning and smart energy-based lightweight urban power load forecasting model for sustainable urban growth

open access: yesFrontiers in Sustainable Cities
IntroductionUrban power load forecasting is essential for smart grid planning but is hindered by data imbalance issues. Traditional single-model approaches fail to address this effectively, while multi-model methods mitigate imbalance by splitting ...
Haewon Byeon   +5 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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