Results 91 to 100 of about 6,077,856 (315)
Performance Analysis and Flow Mechanism of Close-Range Overlapping Rotor in Hover
High payload capacity multi-rotor aerial vehicles are typically configured with multiple propellers to achieve the required aerodynamic lift. However, this design approach often results in an increased overall dimensional envelope, which introduces ...
Ziyi Xu +5 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Simplified Load Distribution Factors for Fiber Reinforced Polymer Composite Bridge Decks
In recent years, researchers have investigated the load distribution factors due to vehicle wheel loads. Several load distribution factors for fiber reinforced polymer deck-steel stringer bridge systems have been proposed.
Woraphot Prachasaree +3 more
doaj +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Energy-Saving Optimization Strategy Research for Chilled Water Units Based on Active Water Storage
An energy-saving optimization operation strategy based on maintaining the high-energy-efficiency operation of chillers is proposed to address the prevalent issue of increased energy consumption in the application of cold-storage technology for economic ...
Huang Junjie +5 more
doaj
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Sacroiliac joint fusion was performed in a patient with a preexisting ipsilateral total hip arthroplasty, with no hip dislocation and unrestricted return to farm work at 3.5 years.
Dustin J. Kress +4 more
doaj +1 more source
IntroductionUrban power load forecasting is essential for smart grid planning but is hindered by data imbalance issues. Traditional single-model approaches fail to address this effectively, while multi-model methods mitigate imbalance by splitting ...
Haewon Byeon +5 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source

