Results 71 to 80 of about 509,208 (268)

Reduced-Order Modeling of Non-Newtonian Fluid Mixing in a Twin-Blade Planetary Mixer Using Data-Driven Singular Value Decomposition

Applied Sciences
Twin-blade planetary mixers are widely employed in the mixing of particle-laden non-Newtonian fluids. Their unique blade configuration makes accurate blade load distribution determination crucial for structural integrity and mixing efficiency.
Fei Huang, Xin-Xiang Fu, Zhi-Chao Ma, Ling Zhao, Yuan Zong   +4 more
doaj   +1 more source

Distribution of cognitive load in Web search [PDF]

Journal of the American Society for Information Science and Technology, 2010
AbstractThe search task and the system both affect the demand on cognitive resources during information search. In some situations the demands may become too high for a person. This article has a three‐fold goal. First, it presents and critiques methods to measure cognitive load.
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Performance Analysis and Flow Mechanism of Close-Range Overlapping Rotor in Hover

Drones
High payload capacity multi-rotor aerial vehicles are typically configured with multiple propellers to achieve the required aerodynamic lift. However, this design approach often results in an increased overall dimensional envelope, which introduces ...
Ziyi Xu, Yi Ding, Zhe Hui, Chu Tang, Zhaobing Jiang, Liang Wang   +5 more
doaj   +1 more source

Distributed load balancing in heterogenous systems

2014 48th Annual Conference on Information Sciences and Systems (CISS), 2014
We consider the problem of distributed load balancing in heterogenous parallel server systems, where the service rate achieved by a user at a server depends on both the user and the server. Such heterogeneity typically arises in wireless networks (e.g., servers may represent frequency bands, and the service rate of a user varies across bands).
Se-Young Yun, Alexandre Proutière
openaire   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Simplified Load Distribution Factors for Fiber Reinforced Polymer Composite Bridge Decks

The Baltic Journal of Road and Bridge Engineering, 2013
In recent years, researchers have investigated the load distribution factors due to vehicle wheel loads. Several load distribution factors for fiber reinforced polymer deck-steel stringer bridge systems have been proposed.
Woraphot Prachasaree, Pongsak Sookmanee, Suchart Limkatanyu, Hota V. S. GangaRao   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source