Results 121 to 130 of about 2,022,327 (302)

Cluster-Based Load Balancing Algorithms for Grids

, 2011
E-science applications may require huge amounts of data and high processing power where grid infrastructures are very suitable for meeting these requirements. The load distribution in a grid may vary leading to the bottlenecks and overloaded sites.
Dagdeviren, Orhan, Erciyes, Kayhan, Payli, Resat Umit   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Changes in human calcaneal morphology throughout the Pleistocene-Holocene Levant

Frontiers in Earth Science
The calcaneal morphology changed considerably during human evolution to enable efficient bipedal locomotion. However, little information exists regarding its adaptation to changes in habitual activities following the transition to a sedentary lifestyle ...
Ariana Dann, Ariana Dann, Ariel Pokhojaev, Ariel Pokhojaev, Ariel Pokhojaev, Marie Anton, Guy Yalovitsky, Guy Yalovitsky, Ruth Kallevag-Pelleg, Ruth Kallevag-Pelleg, Ruth Kallevag-Pelleg, Hila May, Hila May   +12 more
doaj   +1 more source

Consideration of load distribution and native soft tissue anatomy when choosing an animal bony model. [PDF]

Ann Transl Med, 2023
Anastasio AT, Grant C, Peairs EM, Fernandez-Moure JS.   +3 more
europepmc   +1 more source

Use of the WEST-1 wind turbine simulator to predict blade fatigue load distribution [PDF]

To test the ability of WEST-1 to predict blade fatigue load distribution, actual wind signals were fed into the simulator and the response data were recorded and processed in the same manner as actual wind turbine data.
Janetzke, D. C.
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

K-type modification of thread tooth for inverted planetary roller screw mechanism and its effect on load distribution

Journal of Applied Science and Engineering
The transmission performance of the inverted planetary roller screw mechanism (IPRSM) is affected by nonuniform load distribution on the thread tooth.
Xinyu Lv, Yanqiang Sun, Guiping Xie, Huiming Cheng, Lingyan Zhao   +4 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Load distribution after unilateral condylar fracture with shortening of the ramus: a finite element model study. [PDF]

Head Face Med, 2023
Helmer LML, Klop C, Lobbezoo F, de Lange J, Koolstra JH, Dubois L.   +5 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source