Results 91 to 100 of about 177,951 (296)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Short-term load forecasting of urban gas using a hybrid model based on improved fruit fly optimization algorithm and support vector machine

Energy Reports, 2019
The accurate forecasting of short-term load for urban gas is the premise of gas supply sales, pipe network planning, and energy optimization scheduling.
Hongfang Lu, Mohammadamin Azimi, Tom Iseley   +2 more
doaj   +1 more source

Load Forecasting Based Distribution System Network Reconfiguration-A Distributed Data-Driven Approach

, 2017
In this paper, a short-term load forecasting approach based network reconfiguration is proposed in a parallel manner. Specifically, a support vector regression (SVR) based short-term load forecasting approach is designed to provide an accurate load ...
Gu, Yi, Jiang, Huaiguang, Muljadi, Eduard, Solis, Francisco J., Zhang, Jun Jason, Zhang, Yingchen   +5 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

PERAMALAN BEBAN LISTRIK MENGGUNAKAN JARINGAN SARAF TIRUAN METODE KOHONEN [PDF]

, 2010
Electrical energy consumption has an important role in the implementation of development for the welfare and increase economic activity. Thus, necessary for forecasting electricity load menyelenggakan electric power supply business in a number of evenly.
., Setiawardhana, Fariza, Arna, Syeto, Galang   +2 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Differentially Private Clustered Federated Load Prediction Based on the Louvain Algorithm

Algorithms
Load forecasting plays a fundamental role in the new type of power system. To address the data heterogeneity and security issues encountered in load forecasting for smart grids, this paper proposes a load-forecasting framework suitable for residential ...
Tingzhe Pan, Jue Hou, Xin Jin, Chao Li, Xinlei Cai, Xiaodong Zhou   +5 more
doaj   +1 more source

Jaringan Syaraf Tiruan Sebagai Metode Peramalan Beban Listrik Harian Di PT. Pismatex Pekalongan [PDF]

, 2014
Load electricity forecasting of industry can provide an information support to the Top Management and other stakeholders in terms of estimating and monitoring the power requirements and effort in providing it. With the artificial neural network method as
Assaffat, L. (Luqman), Maulidin, M. S. (M)   +1 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source