Results 91 to 100 of about 3,806,141 (312)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Deep Learning for Household Load Forecasting—A Novel Pooling Deep RNN

IEEE Transactions on Smart Grid, 2018
The key challenge for household load forecasting lies in the high volatility and uncertainty of load profiles. Traditional methods tend to avoid such uncertainty by load aggregation (to offset uncertainties), customer classification (to cluster ...
Heng Shi, Minghao Xu, Ran Li
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Intelligent Systems for Power Load Forecasting: A Study Review

Energies, 2020
The study of power load forecasting is gaining greater significance nowadays, particularly with the use and integration of renewable power sources and external power stations. Power forecasting is an important task in the planning, control, and operation
Ibrahim Salem Jahan, Vaclav Snasel, Stanislav Misak   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Classification of load forecasting studies by forecasting problem to select load forecasting techniques and methodologies

, 2018
arXiv ...
Dumas, Jonathan, Cornélusse, Bertrand
openaire   +3 more sources

Hybrid CNN-LSTM Model for Short-Term Individual Household Load Forecasting

IEEE Access, 2020
Power grids are transforming into flexible, smart, and cooperative systems with greater dissemination of distributed energy resources, advanced metering infrastructure, and advanced communication technologies.
Musaed A. Alhussein, Khursheed Aurangzeb, Syed Irtaza Haider   +2 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Short-term load forecasting of urban gas using a hybrid model based on improved fruit fly optimization algorithm and support vector machine

Energy Reports, 2019
The accurate forecasting of short-term load for urban gas is the premise of gas supply sales, pipe network planning, and energy optimization scheduling.
Hongfang Lu, Mohammadamin Azimi, Tom Iseley   +2 more
doaj   +1 more source