Results 41 to 50 of about 26,572 (214)
Meitan xuebaoWith the rapid advancement of the high-speed railway network, it is inevitable that some key lines will cross the mininggoaf site. This poses higher requirements for the construction, safe operation, and maintenance of high-speed railways.
Lianwei REN +5 more
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Control of Vibrations due to Moving Loads on Suspension Bridges
Nonlinear Analysis, 2006 The flexibility and low damping of the long span suspended cables in suspension bridges makes them prone to vibrations due to wind and moving loads which affect the dynamic responses of the suspended cables and the bridge deck.
M. Zribi +2 more
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
TRANSIENT STRESS ANALYSIS OF SIMPLY SUPPORT BEAM EXCITED UNDER MOVING LOAD
Al-Qadisiyah Journal for Engineering Science, 2016 In this paper, an experimental and numerical study of dynamic deflection and dynamic bending stress of beam structure under moving load has been carried out. The moving load is constant in magnitude and travels at a uniform speed. The dynamic analysis of
Saddiq Emad Sadiq, Dr. Ali Raad Hassan
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FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar +7 more
wiley +1 more source
Yantu gongcheng xuebao, 2020 In order to analyze the isolation effectiveness of in-filled trench to the ground vibration caused by subway operation, a coupling model, which is divided into five parts including moving train, track structure, lining, ground and in-filled trench, is ...
CAI Yuan-qiang 1, 2, JIANG Qian-ming 1, CAO Zhi-gang 1, YUAN Zong-hao 2, LOU Jia-yue 3, ZHANG Ying-zhe 3
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Arthritis Care &Research, EarlyView.Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart +5 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli +13 more
wiley +1 more source