Results 41 to 50 of about 262,357 (266)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Typical characteristic mining and load evaluation for the difficulties of power supply–demand balance regulation

open access: yesIET Generation, Transmission & Distribution
Power systems face significant challenges in maintaining power balance because of the stochasticity of sources and loads. This unpredictability makes it difficult to characterize the typical demand for grid power balance regulation, which results in a ...
Junwei Li   +3 more
doaj   +1 more source

Real-time greenhouse gas emission intensity informed demand-side load regulation for power grid decarbonization

open access: yesCell Reports Sustainability
Summary: The US targets net-zero-carbon electricity by 2035, emphasizing the need for both supply- and demand-side strategies in the power sector. Our study focuses on demand-side carbon reduction via load regulation, using real-time greenhouse gas ...
Honglin Li   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Wind turbine participation in micro-grid frequency control through self-tuning, adaptive fuzzy droop in de-loaded area

open access: yesIET Smart Grid, 2019
The purpose of this research is to present an innovative load frequency control in the presence of wind turbines in islanded micro-grid (MG). As islanded MG suffers from low inertia and insufficient primary frequency response (PFR), utilising the ...
Ahmadreza Abazari   +3 more
doaj   +1 more source

Research on the Novel Flexible On-Load Voltage Regulator Transformer and Voltage Stability Analysis

open access: yesEnergies, 2022
Voltage stability has always been a hot topic in power system research. Traditional On-Load Tap-Charger (OLTC) transformer is considered to play a very important role in the system voltage stability.
Libo Han   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Characteristics and Optimization of Transient Process of Pump-Turbine Units in Power Generation Mode

open access: yesEnergies
Pumped storage power is considered an ideal regulated power source for new energy. However, the traditional one-dimensional characteristic line method cannot predict the pulsating pressure caused by the reverse “S” characteristic of a pump–turbine.
Minglu Zhang   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy