Results 51 to 60 of about 262,357 (266)

Regulation of RANKL by biomechanical loading in fibrochondrocytes of meniscus [PDF]

Journal of Biomechanics, 2006
We sought to determine whether fibrochondrocytes from menisci express receptor activator of NF-kappaB (RANK), its ligand (RANKL), or osteoprotegerin (OPG) and, if so, whether their expression is modulated by dynamic mechanical loading under inflammatory and normal conditions.Fibrochondrocytes from rat menisci were subjected to cyclic tensile strain ...
James, Deschner, Ewa, Wypasek, Mario, Ferretti, Birgit, Rath, Mirela, Anghelina, Sudha, Agarwal   +5 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Engineering practice of large-scale millisecond accurate load control system of large power grid

The Journal of Engineering, 2018
Under the background of large-scale development and utilization of clean energy, there are serious security and stability risks and load balance problems in power grids with high penetration of clean energy and high portion of external power supply ...
Hu Haoming, Zhou Qian, Zhang Ningyu, Wei Peng, Cui Zhanfei   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Research on the non-inductive regulation method with load of new energy grid considering carbon emission constraints

Diance yu yibiao
Aiming at the problems of high carbon emission, high generation retarder and low voltage stability margin in load control of power grid with new energy, a non-inductive load regulation method of power system with distributed new energy and carbon ...
HONG Jianjun, GAO Qiang, YAO Huan, SUN Jie   +3 more
doaj   +1 more source

A decentralised bi-level control approach to wind power regulation via thermostatically controlled loads

The Journal of Engineering, 2019
This paper studies the wind power regulation problem by controlling a population of thermostatically controlled loads (TCLs) in smart grids.
H. Xing, P. Zeng, Z. Lin, Q. Wu, M. Fu
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Multi‐round load control method considering the safe electricity consumption for industrial users based on situational awareness

IET Generation, Transmission & Distribution
This paper proposes a situational awareness‐based method of load control for safe electricity consumption by industrial users to assess the risk of regulated load equipment within industrial users and to ensure their safe use of electricity.
Zonghan Chen, Yonghai Xu, Mingming Pan, Tianze Wang, Jindou Yuan, Lin Chen, Shun Tao   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source