Results 81 to 90 of about 278,966 (304)

Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection [PDF]

, 2005
Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality.
Bertoletti, A., Copas, A., Dunn, C., Gilson, R.J., Johnstone, R., Lascar, R.M., Lopes, A.R., Maini, M.K., Reignat, S., Webster, G.   +9 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Dynamic Frequency-Constrained Load Restoration Considering Multi-Phase Cold Load Pickup Behaviors

IEEE Transactions on Power Systems
Cold load pickup (CLPU) behavior has great impacts on power system frequency during load restoration process. The CLPU behavior consists of not only the current inrush with extremely high magnitude in the first several seconds, but also high power demands that can last for minutes or even hours.
Dunjian Xie, Yan Xu, Sivakumar Nadarajan, Vaiyapuri Viswanathan, Amit Kumar Gupta   +4 more
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A collaborative restoration strategy of resilient distribution system with the support of electric bus clusters

International Journal of Electrical Power & Energy Systems
The widespread deployment of electric buses (EBs) offers substantial flexibility resources to support the service restoration and enhance the resilience of distribution system (DS). Therefore, this paper presents a comprehensive and collaborative service
Yina Guo, Kai Liao, Jianwei Yang, Shunwei Zheng, Zhengyou He   +4 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Panama City Fisheries Resources Office: FY 2003 Annual Report [PDF]

, 2004
HIGHLIGHTS FOR FY 2003 1. Continued a 3-year threatened Gulf sturgeon population estimate in the Escambia River, Florida and conducted presence-absence surveys in 4 other Florida river systems and 1 bay. 2. Five juvenile Gulf sturgeon collected, near

core  

Exploiting multi-agent system technology within an autonomous regional active network management system [PDF]

, 2007
This paper describes the proposed application of multi-agent system (MAS) technology within AuRA-NMS, an autonomous regional network management system currently being developed in the UK through a partnership between several UK universities, distribution
Davidson, Euan M., McArthur, Stephen D. J.   +1 more
core   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

A Two‐Stage Emergency Reconfiguration Strategy for Port Cyber‐Physical Systems During Disasters Considering the Marginal Value Quantification of Multi‐Service Information Flows

IET Renewable Power Generation
With the advancement of digitalization, the port is increasingly dependent on cyber systems to coordinate their multiple service operations, gradually evolving into a port cyber‐physical system (PCPS).
Sidun Fang, Mengyang Guo, Guanhong Chen, Tao Niu, Ruijin Liao   +4 more
doaj   +1 more source