Results 51 to 60 of about 503,790 (289)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

多级行星齿轮传动静力学均载研究

open access: yesJixie chuandong, 2012
A calculation model of NGW type planetary gear transmission is established.Considering gear manufacturing and assembling errors,load coefficient of the system is computed by using the theory of equivalent mesh error and the influence of load sharing ...
赵又红   +4 more
doaj  

Research on the Influence of the Interaction between Errors on the Statics Load Sharing Characteristic of Gear Split Torque Transmission System

open access: yesJixie chuandong, 2021
In order to further understand the relationship between the errors and the load sharing performance of the split torque transmission system, the static model and equation of the system are established for the single input double output gear split torque ...
Qibo Wang   +3 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Simple implementation of load-sharing banyan network and its throughput performance

open access: yesElectronics Letters, 1990
An implementation of a load-sharing banyan network based on sorting and routing cells is proposed. Our implementation requires simple management and is easy to diagnose. An iterative algorithm is derived to analyse the throughput performance of the proposed load-sharing banyan network.
openaire   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Performance Evaluation of Fuel Cell and Microturbine as Distributed Generators in a Microgrid [PDF]

open access: yes, 2009
This paper presents dynamic models of distributed generators (DG) and investigates dynamic behaviour of the DG units within a microgrid system. The DG units include micro turbine, fuel cell and the electronically interfaced sources.
Mohamed , Azah   +2 more
core  

Assessing load-sharing within optimistic simulation platforms [PDF]

open access: yes, 2012
The advent of multi-core machines has lead to the need for revising the architecture of modern simulation platforms. One recent proposal we made attempted to explore the viability of load-sharing for optimistic simulators run on top of these types of ...
PELLEGRINI, ALESSANDRO   +2 more
core   +1 more source

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