Results 61 to 70 of about 503,790 (289)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

面齿轮分扭传动系统均载研究

open access: yesJixie chuandong, 2013
The mathematical models of the variable includes nonlinear support stiffness,time-varying meshing stiffness,damping,gear backlash,etc are established to analyze the load sharing performance of the helicopter face gear split torque transmission system,and
赵宁, 王锐锋, 贾清健
doaj  

An Instantaneous Load-Sharing Parallel Control Method Using Improved PWM-Capture With DMA in a Power Conversion System

open access: yesIEEE Access
As power demand from electric vehicles and digital loads increases, the use of direct current power supplies is increasing. As a result, the application of microgrid utilizing various distributed power systems is expanding.
Tae-Whan Park   +2 more
doaj   +1 more source

Secondary Frequency and Voltage Control of Islanded Microgrids via Distributed Averaging [PDF]

open access: yes, 2015
In this work we present new distributed controllers for secondary frequency and voltage control in islanded microgrids. Inspired by techniques from cooperative control, the proposed controllers use localized information and nearest-neighbor communication
Bullo, Francesco   +5 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Analysis of load sharing characteristics of the thermoelastic coupled coaxial face gear power split transmission system

open access: yesJixie chuandong
ObjectiveTaking a coaxial face gear power split transmission system as the research object, the influence of gear thermal deformation induced by the temperature field on stiffness and backlash was considered, and a combined approach of analytical method ...
LIU Li, GUO Hui, ZHAO Ning
doaj   +2 more sources

Dynamic Load Sharing Characteristic of Planetary Transmission Considering Number of Planetary Wheel and Clearance

open access: yesJixie chuandong, 2020
In order to study the influence of the number of planetary wheel and clearance on the dynamic load sharing characteristics of the planetary transmission system, based on the lumped parameter theory, considering the factors such as error, support ...
Dong Hao, Liu Zhiyu, Liu Bo
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

New algorithm for distributed frequency assignments in IEEE 802.11 [PDF]

open access: yes, 2007
The continuous growth of IEEE 802.11 wireless local area networks (WLAN) brings the benefit of a high speed wireless access to packet networks, such as Internet. But it also entails the successive appearance of new unresolved problems.
García Villegas, Eduard   +2 more
core  

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