Results 31 to 40 of about 151,329 (301)
The Bitsadze–Samarskii problem for some characteristically loaded hyperbolic-parabolic equation
The paper considers a characteristically loaded equation of a mixed hyperbolic-parabolic type with degeneration of order in the hyperbolicity part of the domain.
Kazbek Uzeirovich Khubiev
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Boundary value problems for discontinuously loaded parabolic equations
The article deals with boundary value problems for a discontinuously loaded parabolic equation with a Riemann – Liouville fractional integro-differentiation operator with variable coefficients.
Mukhamed M. Karmokov +2 more
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ON SOME PROBLEMS FOR LOADED PARTIAL DIFFERENTIAL EQUATION OF THE FIRST ORDER
For equations of the form ux + uy = lux(x;0) + muy(0;y) the investigation on the correctness of the number of initial value problems in bounded and unbounded domains.
Attaev A. Kh.
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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In this article, we construct exact traveling wave solutions of the loaded Korteweg-de Vries, the loaded modified Korteweg-de Vries, and the loaded Gardner equation by the functional variable method.
Bazar Babajanov, Fakhriddin Abdikarimov
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
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The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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In the paper we study a loaded degenerate hyperbolic equation of the second order with variable coefficients. The principal part of the equation is the Gellerstedt operator.
Anatoly H Attaev
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